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Test-firing ammunition for spliceosome inhibition in cancer.

Test-firing ammunition for spliceosome inhibition in cancer.

http://www.wikidata.org/entity/Q37339144

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Carcinogenic Parasite Secretes Growth Factor That Accelerates Wound Healing and Potentially Promotes Neoplasia Identification of small molecule inhibitors of pre-mRNA splicing.Color-Coded Super-Resolution Small-Molecule Imaging.Small Molecule Modulators of Pre-mRNA Splicing in Cancer Therapy Design and synthesis of analogues of natural products.Meta-analysis of gene expression profiles indicates genes in spliceosome pathway are up-regulated in hepatocellular carcinoma (HCC).Prognostic value of SRSF2 mutations in patients with de novo myelodysplastic syndromes: A meta-analysis.Expression levels of SF3B3 correlate with prognosis and endocrine resistance in estrogen receptor-positive breast cancer.Splicing Factor Mutations in Cancer.

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Test-firing ammunition for spliceosome inhibition in cancer.

http://www.wikidata.org/entity/Q37339144

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 04 October 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Test-firing ammunition for spliceosome inhibition in cancer.

@en

Test-firing ammunition for spliceosome inhibition in cancer.

@nl

type

label

Test-firing ammunition for spliceosome inhibition in cancer.

@en

Test-firing ammunition for spliceosome inhibition in cancer.

@nl

prefLabel

Test-firing ammunition for spliceosome inhibition in cancer.

@en

Test-firing ammunition for spliceosome inhibition in cancer.

@nl

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1078-0432.CCR-13-2461

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Clinical Cancer Research

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Test-firing ammunition for spliceosome inhibition in cancer.

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Scott M Dehm

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Molecular architecture of the multiprotein splicing factor SF3b

Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged

Splicing in disease: disruption of the splicing code and the decoding machinery.

The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region.

Phase I pharmacokinetic and pharmacodynamic study of the first-in-class spliceosome inhibitor E7107 in patients with advanced solid tumors.

mRNA splicing variants: exploiting modularity to outwit cancer therapy

Biologic and clinical significance of somatic mutations of SF3B1 in myeloid and lymphoid neoplasms.

Alternative splicing: a pivotal step between eukaryotic transcription and translation.

Sudemycins, novel small molecule analogues of FR901464, induce alternative gene splicing.

Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.

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6064-6066

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scholarly article

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10.1158/1078-0432.CCR-13-2461

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