Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome
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Therapeutic Targets for Neurodevelopmental Disorders Emerging from Animal Models with Perinatal Immune ActivationNitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation.The 4-cysteine zinc-finger motif of the RNA polymerase regulator DksA serves as a thiol switch for sensing oxidative and nitrosative stress.A role for thrombospondin-1 deficits in astrocyte-mediated spine and synaptic pathology in Down's syndrome.Trafficking of immune cells in the central nervous systemQuantitative mass spectrometry-based proteomics reveals the dynamic range of primary mouse astrocyte protein secretionIdentification of astrocyte secreted proteins with a combination of shotgun proteomics and bioinformatics.Calcineurin and glial signaling: neuroinflammation and beyondAstrocytes directly influence tumor cell invasion and metastasis in vivo.Exposure to inflammatory cytokines IL-1β and TNFα induces compromise and death of astrocytes; implications for chronic neuroinflammation.The ROP vesicle release factor is required in adult Drosophila glia for normal circadian behavior.Proteomic analysis of stromal proteins in different stages of colorectal cancer establishes Tenascin-C as a stromal biomarker for colorectal cancer metastasis.Plasminogen activator inhibitor type 1 regulates microglial motility and phagocytic activity.TIMP-1 couples RhoK activation to IL-1β-induced astrocyte responsesRegulation of brain glutamate metabolism by nitric oxide and S-nitrosylationGFAP expression as an indicator of disease severity in mouse models of Alexander disease.Mutant copper-zinc superoxide dismutase (SOD1) induces protein secretion pathway alterations and exosome release in astrocytes: implications for disease spreading and motor neuron pathology in amyotrophic lateral sclerosisSite specific identification of endogenous S-nitrosocysteine proteomesMass Spectrometry-based Proteomics and Peptidomics for Systems Biology and Biomarker Discovery.Combined analysis of the glia secretome and the CSF proteome: neuroinflammation and novel biomarkers.Mapping of the secretome of primary isolates of mammalian cells, stem cells and derived cell lines.Mass spectrometry-based identification of S-nitrosocysteine in vivo using organic mercury assisted enrichmentTight junctions at the blood brain barrier: physiological architecture and disease-associated dysregulation.Glia-based biomarkers and their functional role in the CNS.Proteome of brain glia: the molecular basis of diverse glial phenotypes.Gypenoside IX Suppresses p38 MAPK/Akt/NFκB Signaling Pathway Activation and Inflammatory Responses in Astrocytes Stimulated by Proinflammatory Mediators.Crosstalk between glial and glioblastoma cells triggers the "go-or-grow" phenotype of tumor cells.Nitric oxide counteracts the hyperoxia-induced proliferation and proinflammatory responses of mouse astrocytes.Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis.A proteomic analysis of PKCε targets in astrocytes: implications for astrogliosis.Physiology of Astroglia.
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P2860
Mass spectrometric and computational analysis of cytokine-induced alterations in the astrocyte secretome
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Mass spectrometric and computa ...... ons in the astrocyte secretome
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Mass spectrometric and computa ...... ns in the astrocyte secretome.
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type
label
Mass spectrometric and computa ...... ons in the astrocyte secretome
@en
Mass spectrometric and computa ...... ns in the astrocyte secretome.
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Mass spectrometric and computa ...... ons in the astrocyte secretome
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Mass spectrometric and computa ...... ns in the astrocyte secretome.
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P2093
P2860
P50
P356
P1433
P1476
Mass spectrometric and computa ...... ons in the astrocyte secretome
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David W Speicher
Harry Ischiropoulos
Ioannis Parastatidis
Rita J Balice-Gordon
Sarah Dunn Keene
P2860
P304
P356
10.1002/PMIC.200800385
P577
2009-02-01T00:00:00Z