Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.
about
Of mice, cattle, and humans: the immunology and treatment of river blindnessA novel bacterial symbiont in the nematode Spirocerca lupiDoxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasisDoxycycline plus ivermectin versus ivermectin alone for treating onchocerciasisRepurposing drugs for the treatment and control of helminth infectionsImmunization with L. sigmodontis microfilariae reduces peripheral microfilaraemia after challenge infection by inhibition of filarial embryogenesisTissue and stage-specific distribution of Wolbachia in Brugia malayiImmunization of Mastomys coucha with Brugia malayi recombinant trehalose-6-phosphate phosphatase results in significant protection against homologous challenge infectionA cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets WolbachiaResearch for new drugs for elimination of onchocerciasis in AfricaKilling filarial nematode parasites: role of treatment options and host immune responseComparison of Doxycycline, Minocycline, Doxycycline plus Albendazole and Albendazole Alone in Their Efficacy against Onchocerciasis in a Randomized, Open-Label, Pilot TrialImmunisation with a multivalent, subunit vaccine reduces patent infection in a natural bovine model of onchocerciasis during intense field exposureAsymmetric Wolbachia segregation during early Brugia malayi embryogenesis determines its distribution in adult host tissuesThe heme biosynthetic pathway of the obligate Wolbachia endosymbiont of Brugia malayi as a potential anti-filarial drug targetImmunoepidemiological profiling of onchocerciasis patients reveals associations with microfilaria loads and ivermectin intake on both individual and community levelsEffect of Two or Six Doses 800 mg of Albendazole Every Two Months on Loa loa Microfilaraemia: A Double Blind, Randomized, Placebo-Controlled TrialPatients with nodding syndrome in Uganda improve with symptomatic treatment: a cross-sectional studyShort-Course, High-Dose Rifampicin Achieves Wolbachia Depletion Predictive of Curative Outcomes in Preclinical Models of Lymphatic Filariasis and Onchocerciasis.Macrofilaricidal activity after doxycycline only treatment of Onchocerca volvulus in an area of Loa loa co-endemicity: a randomized controlled trial.Lymphatic vascularisation and involvement of Lyve-1+ macrophages in the human onchocerca nodule.Repositioning of an existing drug for the neglected tropical disease Onchocerciasis.Infection with Mansonella perstans Nematodes in Buruli Ulcer Patients, GhanaModelling the impact of ivermectin on River Blindness and its burden of morbidity and mortality in African Savannah: EpiOncho projections.Sustainable control of onchocerciasis: ocular pathology in onchocerciasis patients treated annually with ivermectin for 23 years: a cohort study.Metabolomics-based discovery of diagnostic biomarkers for onchocerciasis.Interaction of a Wolbachia WSP-like protein with a nuclear-encoded protein of Brugia malayi.The Wolbachia endosymbiont as an anti-filarial nematode targetImmunohistological studies on neoplasms of female and male Onchocerca volvulus: filarial origin and absence of Wolbachia from tumor cellsOnchocerciasis: the role of Wolbachia bacterial endosymbionts in parasite biology, disease pathogenesis, and treatment.Lipoprotein biosynthesis as a target for anti-Wolbachia treatment of filarial nematodes.A research agenda for helminth diseases of humans: modelling for control and elimination.A murine macrofilaricide pre-clinical screening model for onchocerciasis and lymphatic filariasisOnchocerca armillata contains the endosymbiotic bacterium Wolbachia and elicits a limited inflammatory response.A randomized trial of doxycycline for Mansonella perstans infection.Filariasis and lymphoedema.A potential role for the interaction of Wolbachia surface proteins with the Brugia malayi glycolytic enzymes and cytoskeleton in maintenance of endosymbiosisPotential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with WolbachiaHyperreactive onchocerciasis is characterized by a combination of Th17-Th2 immune responses and reduced regulatory T cells.River blindness: an old disease on the brink of elimination and control
P2860
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P2860
Wolbachia endobacteria depletion by doxycycline as antifilarial therapy has macrofilaricidal activity in onchocerciasis: a randomized placebo-controlled study.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@en
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@nl
type
label
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@en
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@nl
prefLabel
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@en
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@nl
P2093
P2860
P50
P921
P1476
Wolbachia endobacteria depleti ...... ized placebo-controlled study.
@en
P2093
Alexander Yaw Debrah
Anna Albers
Dietrich W Büttner
John Larbi
Linda Batsa
Marcelle Büttner
Norbert Brattig
Ohene Adjei
Peter Konadu
Rolf Fimmers
P2860
P2888
P304
P356
10.1007/S00430-007-0062-1
P577
2007-11-13T00:00:00Z