A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
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Autoubiquitination of the 26S proteasome on Rpn13 regulates breakdown of ubiquitin conjugatesReceptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells.Dissecting the expression landscape of RNA-binding proteins in human cancersHUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.mTORC2 promotes cell survival through c-Myc-dependent up-regulation of E2F1.Ribosome biogenesis dysfunction leads to p53-mediated apoptosis and goblet cell differentiation of mouse intestinal stem/progenitor cellsThe function of Shoc2: A scaffold and beyond.MDM2 restrains estrogen-mediated AKT activation by promoting TBK1-dependent HPIP degradationAn heregulin-EGFR-HER3 autocrine signaling axis can mediate acquired lapatinib resistance in HER2+ breast cancer models.Evading apoptosis in cancer.Cell death controlling complexes and their potential therapeutic role.HUWE1 interacts with PCNA to alleviate replication stress.Sally Kornbluth: Nature's incredible contraptions.A comprehensive and high-resolution genome-wide response of p53 to stress.Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma.Increased expression of E3 ubiquitin ligases targeting p53 in CLL patients with wild-type TP53 exhibits associations with clinical features of the disease.Reducing histone acetylation rescues cognitive deficits in a mouse model of Fragile X syndrome.HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development
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P2860
A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 07 May 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A network of substrates of the ...... poptosis independently of p53.
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A network of substrates of the ...... poptosis independently of p53.
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type
label
A network of substrates of the ...... poptosis independently of p53.
@en
A network of substrates of the ...... poptosis independently of p53.
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prefLabel
A network of substrates of the ...... poptosis independently of p53.
@en
A network of substrates of the ...... poptosis independently of p53.
@nl
P2093
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A network of substrates of the ...... apoptosis independently of p53
@en
P2093
Jiyeon Kim
Joseph E Lucas
Joseph Geradts
Manabu Kurokawa
Mark W Dewhirst
Neil L Spector
Sally Kornbluth
Thomas J Ribar
P2860
P356
10.1126/SCISIGNAL.2003741
P577
2013-05-07T00:00:00Z