GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.
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The endoplasmic reticulum stress response in aging and age-related diseasesEndoplasmic reticulum stress and the inflammatory basis of metabolic diseaseSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsRole of endoplasmic reticulum stress in drug-induced toxicityThe Role of Organelle Stresses in Diabetes Mellitus and Obesity: Implication for TreatmentEnergy metabolism in the liverXenobiotic perturbation of ER stress and the unfolded protein responseStress management: How the unfolded protein response impacts fatty liver diseaseLipid biology of breast cancerInvolvement of the IRE1α-XBP1 pathway and XBP1s-dependent transcriptional reprogramming in metabolic diseasesEndoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseasesSchisandrin B: A Double-Edged Sword in Nonalcoholic Fatty Liver DiseaseInflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologiesDefining hepatic dysfunction parameters in two models of fatty liver disease in zebrafish larvaeActivating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafishChaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpressionhnRNP A1 mediates the activation of the IRES-dependent SREBP-1a mRNA translation in response to endoplasmic reticulum stressVaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78/MTJ-1 complexPIASy-mediated sumoylation of SREBP1c regulates hepatic lipid metabolism upon fasting signalingCalorie-induced ER stress suppresses uroguanylin satiety signaling in diet-induced obesityMechanisms for insulin resistance: common threads and missing linksAdipose tissue dysfunction and hypertriglyceridemia: mechanisms and management.Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) conThe BiP molecular chaperone plays multiple roles during the biogenesis of torsinA, an AAA+ ATPase associated with the neurological disease early-onset torsion dystonia.Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance.Obesity-induced hepatic steatosis is mediated by endoplasmic reticulum stress in the subfornical organ of the brainHepatic rhythmicity of endoplasmic reticulum stress is disrupted in perinatal and adult mice models of high-fat diet-induced obesityPathogenesis of non-alcoholic fatty liver disease.ER stress and hepatic lipid metabolism.PGRN induces impaired insulin sensitivity and defective autophagy in hepatic insulin resistanceSterol regulatory element-binding protein-1c orchestrates metabolic remodeling of white adipose tissue by caloric restrictionmTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis.Molecularly defined unfolded protein response subclasses have distinct correlations with fatty liver disease in zebrafish.Novel NBAS mutations and fever-related recurrent acute liver failure in Chinese children: a retrospective studyEndoplasmic reticulum stress mediates amyloid β neurotoxicity via mitochondrial cholesterol traffickingAnalysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection.Apolipoprotein B100 quality control and the regulation of hepatic very low density lipoprotein secretion.The endothelial cell receptor GRP78 is required for mucormycosis pathogenesis in diabetic mice.Regulation of basal cellular physiology by the homeostatic unfolded protein responseProteomic and genomic studies of non-alcoholic fatty liver disease--clues in the pathogenesis
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GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@en
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@nl
type
label
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@en
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@nl
prefLabel
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@en
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@nl
P2093
P2860
P50
P356
P1476
GRP78 expression inhibits insu ...... ces hepatic steatosis in mice.
@en
P2093
Hervé Chabanon
Hélène L Kammoun
Isabelle Hainault
Tatsuro Koike
P2860
P304
P356
10.1172/JCI37007
P407
P577
2009-04-13T00:00:00Z