Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
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Inherited Disease Genetics Improves the Identification of Cancer-Associated GenesInsights into cancer severity from biomolecular interaction mechanisms.Structure-Based Analysis Reveals Cancer Missense Mutations Target Protein Interaction InterfacesA Data Fusion Approach to Enhance Association Study in Epilepsy.The Subclonal Architecture of Metastatic Breast Cancer: Results from a Prospective Community-Based Rapid Autopsy Program "CASCADE".MutationAligner: a resource of recurrent mutation hotspots in protein domains in cancer.Coevolution of RAC Small GTPases and their Regulators GEF Proteins.An Atlas of the Human Kinome Reveals the Mutational Landscape Underlying Dysregulated Phosphorylation Cascades in Cancer.3D clusters of somatic mutations in cancer reveal numerous rare mutations as functional targets.Comparison of algorithms for the detection of cancer drivers at subgene resolution.Identification and analysis of mutational hotspots in oncogenes and tumour suppressors.Functional variomics and network perturbation: connecting genotype to phenotype in cancer.mutation3D: Cancer Gene Prediction Through Atomic Clustering of Coding Variants in the Structural Proteome.Decreased FOXJ1 expression and its ciliogenesis programme in aggressive ependymoma and choroid plexus tumours.Distribution bias analysis of germline and somatic single-nucleotide variations that impact protein functional site and neighboring amino acids.Genetic variants affecting equivalent protein family positions reflect human diversity.Aggregation of population-based genetic variation over protein domain homologues and its potential use in genetic diagnostics.Recon3D enables a three-dimensional view of gene variation in human metabolism.Systematic characterization of pan-cancer mutation clusters.
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P2860
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 September 2015
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@en
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@nl
type
label
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@en
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@nl
prefLabel
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@en
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@nl
P2093
P2860
P50
P1433
P1476
Pan-Cancer Analysis of Mutation Hotspots in Protein Domains.
@en
P2093
Anil Korkut
Chris Sander
Jianjiong Gao
Nicholas P Gauthier
P2860
P304
P356
10.1016/J.CELS.2015.08.014
P577
2015-09-23T00:00:00Z