Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10
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Ontogeny of recognition specificity and functionality for the broadly neutralizing anti-HIV antibody 4E10HIV-Host Interactions: Implications for Vaccine DesignEmerging Vaccine TechnologiesStructural insights on the role of antibodies in HIV-1 vaccine and therapyStructure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimerProgress in HIV-1 vaccine development.Humanized Immunoglobulin Mice: Models for HIV Vaccine Testing and Studying the Broadly Neutralizing Antibody Problem.Generation of Long-Lived Bone Marrow Plasma Cells Secreting Antibodies Specific for the HIV-1 gp41 Membrane-Proximal External Region in the Absence of Polyreactivity.Broad and potent cross clade neutralizing antibodies with multiple specificities in the plasma of HIV-1 subtype C infected individuals.HIV-1 Envelope Trimer Design and Immunization Strategies To Induce Broadly Neutralizing Antibodies.Epitope target structures of Fc-mediated effector function during HIV-1 acquisition.Autoreactivity in HIV-1 broadly neutralizing antibodies: implications for their function and induction by vaccination.AIDS/HIV. Host controls of HIV neutralizing antibodies.HIV-1 Env-specific memory and germinal center B cells in C57BL/6 micePolyreactivity and autoreactivity among HIV-1 antibodies.HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design.Crystallographic Identification of Lipid as an Integral Component of the Epitope of HIV Broadly Neutralizing Antibody 4E10.Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice.Human Rhinovirus Presenting 4E10 Epitope of HIV-1 MPER Elicits Neutralizing Antibodies in Human ICAM-1 Transgenic MiceFunctional Versatility of AGY Serine Codons in Immunoglobulin Variable Region Genes.Progress toward active or passive HIV-1 vaccination.Differential Antibody Responses to Conserved HIV-1 Neutralizing Epitopes in the Context of Multivalent Scaffolds and Native-Like gp140 Trimers.Enhanced antibody responses to an HIV-1 membrane-proximal external region antigen in mice reconstituted with cultured lymphocytes.Adeno-associated virus delivery of broadly neutralizing antibodiesImmune System Regulation in the Induction of Broadly Neutralizing HIV-1 Antibodies.New approaches to HIV vaccine development.HIV-1 envelope glycoprotein immunogens to induce broadly neutralizing antibodies.Breaching peripheral tolerance promotes the production of HIV-1-neutralizing antibodies.Peripheral Membrane Interactions Boost the Engagement by an Anti-HIV-1 Broadly Neutralizing Antibody.Human Ig knockin mice to study the development and regulation of HIV-1 broadly neutralizing antibodies.Antibody-virus co-evolution in HIV infection: paths for HIV vaccine development.Immunologic characteristics of HIV-infected individuals who make broadly neutralizing antibodies.Host controls of HIV broadly neutralizing antibody development.Immunological tolerance as a barrier to protective HIV humoral immunity.Potent and broad HIV-neutralizing antibodies in memory B cells and plasma.Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies.What Are the Primary Limitations in B-Cell Affinity Maturation, and How Much Affinity Maturation Can We Drive with Vaccination? Breaking through Immunity's Glass Ceiling.HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design.
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Immune tolerance negatively regulates B cells in knock-in mice expressing broadly neutralizing HIV antibody 4E10
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Immune tolerance negatively re ...... neutralizing HIV antibody 4E10
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Immune tolerance negatively re ...... eutralizing HIV antibody 4E10.
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type
label
Immune tolerance negatively re ...... neutralizing HIV antibody 4E10
@en
Immune tolerance negatively re ...... eutralizing HIV antibody 4E10.
@nl
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Immune tolerance negatively re ...... neutralizing HIV antibody 4E10
@en
Immune tolerance negatively re ...... eutralizing HIV antibody 4E10.
@nl
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Immune tolerance negatively re ...... neutralizing HIV antibody 4E10
@en
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Anthony B Cooper
Colleen Doyle-Cooper
David Nemazee
Dennis R Burton
Krystalyn E Hudson
Michael B Zwick
Patrick Skog
Phillip E Dawson
Takayuki Ota
William R Schief
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P304
P356
10.4049/JIMMUNOL.1301285
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P577
2013-08-12T00:00:00Z