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Food-associated stimuli enhance barrier properties of gastrointestinal mucusParacetamol as a Post Prandial Marker for Gastric Emptying, A Food-Drug Interaction on AbsorptionCase studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data.Utility of physiologically based modeling and preclinical in vitro/in vivo data to mitigate positive food effect in a BCS class 2 compound.In vitro and in vivo pharmacokinetic characterizations of AMG 900, an orally bioavailable small molecule inhibitor of aurora kinases.Population pharmacokinetic modeling of itraconazole and hydroxyitraconazole for oral SUBA-itraconazole and sporanox capsule formulations in healthy subjects in fed and fasted states.Mechanisms underlying food-drug interactions: inhibition of intestinal metabolism and transport.Predicting pharmacokinetics of drugs using physiologically based modeling--application to food effectsEfficacy of OZ439 (artefenomel) against early Plasmodium falciparum blood-stage malaria infection in healthy volunteers.Summary workshop report: bioequivalence, biopharmaceutics classification system, and beyond.Mechanism-Based Modeling of Gastric Emptying Rate and Gallbladder Emptying in Response to Caloric Intake.From bench to humans: formulation development of a poorly water soluble drug to mitigate food effectFixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability.Has nanotechnology led to improved therapeutic outcomes?Drug release from matrix tablets: physiological parameters and the effect of food.Mechanistic prediction of food effects for Compound A tablet using PBPK model.Deciphering nifedipine in vivo delivery from modified release dosage forms: Identification of food effect.Investigation of the effect of food and omeprazole on the relative bioavailability of a single oral dose of 240 mg faldaprevir, a selective inhibitor of HCV NS3/4 protease, in an open-label, randomized, three-way cross-over trial in healthy participDevelopment of population pharmacokinetics model of icotinib with non-linear absorption characters in healthy Chinese volunteers to assess the CYP2C19 polymorphism and food-intake effect.Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor.Food Effect in Humans: Predicting the Risk Through In Vitro Dissolution and In Vivo Pharmacokinetic Models.Effects of food intake on pharmacokinetics of mosapride in beagle dogs.Understanding pharmacokinetic food effects using molecular dynamics simulation coupled with physiologically based pharmacokinetic modeling.Formulation strategy towards minimizing viscosity mediated negative food effect on disintegration and dissolution of immediate release tablets.Predictive Performance of Physiologically Based Pharmacokinetic Models for the Effect of Food on Oral Drug Absorption: Current Status.Effects of High- and Low-Fat Meals on the Pharmacokinetics of Ozanimod, a Novel Sphingosine-1-Phosphate Receptor Modulator.Pharmacokinetics, pharmacodynamics and food effect of LB30870, a novel direct thrombin inhibitor, after single oral doses in healthy men.A phase 1 study to evaluate effect of food on veliparib pharmacokinetics and relative bioavailability in subjects with solid tumors.Effect of food intake on the pharmacokinetics of sarpogrelate and its active metabolite following oral administration to beagle dogs.The minimal impact of food on the pharmacokinetics of ridaforolimus.Effect of the timing of food intake on the absorption and bioavailability of carbamazepine immediate-release tablets in beagle dogs.Lack of significant food effect on the pharmacokinetics of ticagrelor in healthy volunteers.Food Effect on Oral Bioavailability: Old and New Questions.Evaluation of the effect of food and gastric pH on the single-dose pharmacokinetics of cabozantinib in healthy adult subjects.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 24 May 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Current methods for predicting human food effect.
@en
Current methods for predicting human food effect.
@nl
type
label
Current methods for predicting human food effect.
@en
Current methods for predicting human food effect.
@nl
prefLabel
Current methods for predicting human food effect.
@en
Current methods for predicting human food effect.
@nl
P2860
P1433
P1476
Current methods for predicting human food effect.
@en
P2093
Kimberley A Lentz
P2860
P2888
P304
P356
10.1208/S12248-008-9025-8
P407
P577
2008-05-24T00:00:00Z
P5875
P6179
1047012088