Role of calcium-independent phospholipase A(2)β in human pancreatic islet β-cell apoptosis.
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Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processesCharacterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetesEvidence of contribution of iPLA2β-mediated events during islet β-cell apoptosis due to proinflammatory cytokines suggests a role for iPLA2β in T1D development.Glucotoxic and diabetic conditions induce caspase 6-mediated degradation of nuclear lamin A in human islets, rodent islets and INS-1 832/13 cellsInhibition of Ca2+-independent phospholipase A2β (iPLA2β) ameliorates islet infiltration and incidence of diabetes in NOD mice.Glucolipotoxicity impairs ceramide flow from the endoplasmic reticulum to the Golgi apparatus in INS-1 β-cellsGroup VIA Phospholipase A2 (iPLA2β) Modulates Bcl-x 5'-Splice Site Selection and Suppresses Anti-apoptotic Bcl-x(L) in β-Cells.Disruption of Golgi morphology and altered protein glycosylation in PLA2G6-associated neurodegenerationCalcium-independent phospholipases A2 and their roles in biological processes and diseases.Distinct differences in the responses of the human pancreatic β-cell line EndoC-βH1 and human islets to proinflammatory cytokines.Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories.Genetic modulation of islet β-cell iPLA₂β expression provides evidence for its impact on β-cell apoptosis and autophagyPolarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2)
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Role of calcium-independent phospholipase A(2)β in human pancreatic islet β-cell apoptosis.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 October 2012
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Role of calcium-independent phospholipase A
@nl
Role of calcium-independent ph ...... reatic islet β-cell apoptosis.
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type
label
Role of calcium-independent phospholipase A
@nl
Role of calcium-independent ph ...... reatic islet β-cell apoptosis.
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prefLabel
Role of calcium-independent phospholipase A
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Role of calcium-independent ph ...... reatic islet β-cell apoptosis.
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P2093
P2860
P1476
Role of calcium-independent ph ...... reatic islet β-cell apoptosis.
@en
P2093
Alan Bohrer
Sasanka Ramanadham
Sheng Zhang
Suzanne E Barbour
Xiaoyong Lei
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P304
P356
10.1152/AJPENDO.00234.2012
P577
2012-10-16T00:00:00Z