Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.
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Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.PD-L1 blockade effectively restores strong graft-versus-leukemia effects without graft-versus-host disease after delayed adoptive transfer of T-cell receptor gene-engineered allogeneic CD8+ T cells.Primed tumor-reactive multifunctional CD62L+ human CD8+ T cells for immunotherapyVisualization of immune response kinetics in full allogeneic chimeras.Inducible T-cell receptor expression in precursor T cells for leukemia control.PLZF confers effector functions to donor T cells that preserve graft-versus-tumor effects while attenuating GVHDGenetically engineered donor T cells to optimize graft-versus-tumor effects across MHC barriers.The role of dendritic cells in graft-versus-tumor effectImmunomodulation with dendritic cells and donor lymphocyte infusion converge to induce graft vs neuroblastoma reactions without GVHD after allogeneic bone marrow transplantation.SHP-1 Acts as a Key Regulator of Alloresponses by Modulating LFA-1-Mediated Adhesion in Primary Murine T Cells.CAR T cell therapy for multiple myeloma: where are we now and where are we headed?Stop and go: hematopoietic cell transplantation in the era of chimeric antigen receptor T cells and checkpoint inhibitors.
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P2860
Donor T cells primed on leukemia lysate-pulsed recipient APCs mediate strong graft-versus-leukemia effects across MHC barriers in full chimeras.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 30 January 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Donor T cells primed on leukem ...... MHC barriers in full chimeras.
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Donor T cells primed on leukem ...... MHC barriers in full chimeras.
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type
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Donor T cells primed on leukem ...... MHC barriers in full chimeras.
@en
Donor T cells primed on leukem ...... MHC barriers in full chimeras.
@nl
prefLabel
Donor T cells primed on leukem ...... MHC barriers in full chimeras.
@en
Donor T cells primed on leukem ...... MHC barriers in full chimeras.
@nl
P2093
P2860
P50
P1433
P1476
Donor T cells primed on leukem ...... MHC barriers in full chimeras
@en
P2093
Bruce R Blazar
Karl Welte
Martin G Sauer
Martin Hapke
Rolf Baumann
Verena Schlaphoff
Wolfgang Koestner
P2860
P304
P356
10.1182/BLOOD-2008-09-181677
P407
P577
2009-01-30T00:00:00Z