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Transmission distortion affecting human noncrossover but not crossover recombination: a hidden source of meiotic driveVariants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populationsPRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humansMolecular evolution of genes in avian genomesDistribution of recombination hotspots in the human genome--a comparison of computer simulations with real dataGenetic crossovers are predicted accurately by the computed human recombination mapConservation of recombination hotspots in yeast.The case of the fickle fingers: how the PRDM9 zinc finger protein specifies meiotic recombination hotspots in humans.Recombination drives vertebrate genome contraction.Contrasting methods of quantifying fine structure of human recombination.High diversity at PRDM9 in chimpanzees and bonobosZinc finger binding motifs do not explain recombination rate variation within or between species of Drosophila.Extensive recombination rate variation in the house mouse species complex inferred from genetic linkage maps.PRDM9 drives evolutionary erosion of hotspots in Mus musculus through haplotype-specific initiation of meiotic recombination.Evolution of the genomic recombination rate in murid rodents.Strong artificial selection in domestic mammals did not result in an increased recombination rate.Crossovers are associated with mutation and biased gene conversion at recombination hotspotsMammalian recombination hot spots: properties, control and evolution.DNA sequence-mediated, evolutionarily rapid redistribution of meiotic recombination hotspots.The sex-specific impact of meiotic recombination on nucleotide composition.The repatterning of eukaryotic genomes by random genetic driftGenetic variants in REC8, RNF212, and PRDM9 influence male recombination in cattle.CD24 is a genetic modifier for risk and progression of prostate cancer.Recombination rate variation in closely related species.Conservation of neutral substitution rate and substitutional asymmetries in mammalian genes.Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila.Reconstructing past changes in locus-specific recombination rates.Meiotic recombination strongly influences GC-content evolution in short regions in the mouse genome.The Red Queen model of recombination hot-spot evolution: a theoretical investigation.Variation in crossover rates across a 3-Mb contig of bread wheat (Triticum aestivum) reveals the presence of a meiotic recombination hotspot.Fine-Scale Recombination Maps of Fungal Plant Pathogens Reveal Dynamic Recombination Landscapes and Intragenic Hotspots.Even small SNP clusters are non-randomly distributed: is this evidence of mutational non-independence?Using human demographic history to infer natural selection reveals contrasting patterns on different families of immune genes.
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description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 06 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The rise and fall of a human recombination hot spot.
@en
The rise and fall of a human recombination hot spot.
@nl
type
label
The rise and fall of a human recombination hot spot.
@en
The rise and fall of a human recombination hot spot.
@nl
prefLabel
The rise and fall of a human recombination hot spot.
@en
The rise and fall of a human recombination hot spot.
@nl
P2860
P356
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The rise and fall of a human recombination hot spot.
@en
P2093
Alec J Jeffreys
Rita Neumann
P2860
P2888
P304
P356
10.1038/NG.346
P407
P577
2009-04-06T00:00:00Z