Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production.
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Structure-function analysis of HKE4, a member of the new LIV-1 subfamily of zinc transportersZinc metallothionein imported into liver mitochondria modulates respirationChromium(VI) down-regulates heavy metal-induced metallothionein gene transcription by modifying transactivation potential of the key transcription factor, metal-responsive transcription factor 1Detrimental or beneficial: the role of TRPM2 in ischemia/reperfusion injuryGlutamate receptor ion channels: structure, regulation, and functionp38 activation is required upstream of potassium current enhancement and caspase cleavage in thiol oxidant-induced neuronal apoptosisMicrosomal glutathione transferase 1 protects against toxicity induced by silica nanoparticles but not by zinc oxide nanoparticlesPeroxynitrite-induced neuronal apoptosis is mediated by intracellular zinc release and 12-lipoxygenase activationComparison of the mechanism of toxicity of zinc oxide and cerium oxide nanoparticles based on dissolution and oxidative stress propertiesHydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truthChronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons.Injured Fluoro-Jade-positive hippocampal neurons contain high levels of zinc after traumatic brain injury.Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model.Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cordZn2+ activates large conductance Ca2+-activated K+ channel via an intracellular domain.The changing landscape of ischaemic brain injury mechanisms.Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice.Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicityAlpha-ketoglutarate dehydrogenase: a target and generator of oxidative stressERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity.Obligatory role of ASK1 in the apoptotic surge of K+ currents.Zinc accumulation after target loss: an early event in retrograde degeneration of thalamic neuronsZinc in innate and adaptive tumor immunity.Protective antioxidant and antiapoptotic effects of ZnCl2 in rat pancreatic islets cultured in low and high glucose concentrations.Angiotensin II potentiates zinc-induced cortical neuronal death by acting on angiotensin II type 2 receptorTraumatic brain injury: developmental differences in glutamate receptor response and the impact on treatment.Familial amyotrophic lateral sclerosis.Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturationMetabotropic glutamate receptor subtype 5 antagonists MPEP and MTEP.TRPM2 channel deficiency prevents delayed cytosolic Zn2+ accumulation and CA1 pyramidal neuronal death after transient global ischemiaZn²+ chelation improves recovery by delaying spreading depression-like events.Modulation of mitochondrial function by endogenous Zn2+ pools.Biphasic modulation of ryanodine receptors by sulfhydryl oxidation in rat ventricular myocytesZinc modulation of glycine receptorsMechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons.Exposure of neurons to excitotoxic levels of glutamate induces cleavage of the RNA editing enzyme, adenosine deaminase acting on RNA 2, and loss of GLUR2 editing.Mechanism(s) of Toxic Action of Zn and Selenite: A Study on AS-30D Hepatoma Cells and Isolated MitochondriaZinc-permeable ion channels: effects on intracellular zinc dynamics and potential physiological/pathophysiological significance.Redox regulation of intracellular zinc: molecular signaling in the life and death of neuronsSynaptically released zinc triggers metabotropic signaling via a zinc-sensing receptor in the hippocampus.
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P2860
Preferential Zn2+ influx through Ca2+-permeable AMPA/kainate channels triggers prolonged mitochondrial superoxide production.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1999
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@en
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@nl
type
label
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@en
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@nl
prefLabel
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@en
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@nl
P2093
P2860
P356
P1476
Preferential Zn2+ influx throu ...... ondrial superoxide production.
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.5.2414
P407
P577
1999-03-01T00:00:00Z