C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats
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The human SWI/SNF subunit Brm is a regulator of alternative splicingCDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain RepeatThe transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription.Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation.Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7.Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters.Cdc28 kinase activity regulates the basal transcription machinery at a subset of genes.The Spt4p subunit of yeast DSIF stimulates association of the Paf1 complex with elongating RNA polymerase II.Fcp1 directly recognizes the C-terminal domain (CTD) and interacts with a site on RNA polymerase II distinct from the CTD.Molecular components of the circadian clock in mammalsBRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domainThe role of Ctk1 kinase in termination of small non-coding RNAsUp-regulation of P-TEFb by the MEK1-extracellular signal-regulated kinase signaling pathway contributes to stimulated transcription elongation of immediate early genes in neuroendocrine cellsThreonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongationVariant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias.RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and TemplateProgression through the RNA polymerase II CTD cycleTranscriptional architecture and chromatin landscape of the core circadian clock in mammalsERK1/2-mediated phosphorylation of small hepatitis delta antigen at serine 177 enhances hepatitis delta virus antigenomic RNA replicationA novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.Phosphorylation-regulated binding of RNA polymerase II to fibrous polymers of low-complexity domains.Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase IIIYeast screens identify the RNA polymerase II CTD and SPT5 as relevant targets of BRCA1 interaction.Predikin and PredikinDB: a computational framework for the prediction of protein kinase peptide specificity and an associated database of phosphorylation sitesPhosphorylation by Cak1 regulates the C-terminal domain kinase Ctk1 in Saccharomyces cerevisiae.Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.The phosphoCTD-interacting domain of Topoisomerase IRNA polymerase II transcription elongation and Pol II CTD Ser2 phosphorylation: A tail of two kinases.CDK8 is a positive regulator of transcriptional elongation within the serum response network.Involvement of cyclin K posttranscriptional regulation in the formation of Artemia diapause cystsEnhancer RNA facilitates NELF release from immediate early genesCyclin-dependent kinase 9 (Cdk9) of fission yeast is activated by the CDK-activating kinase Csk1, overlaps functionally with the TFIIH-associated kinase Mcs6, and associates with the mRNA cap methyltransferase Pcm1 in vivoA rule-based kinetic model of RNA polymerase II C-terminal domain phosphorylation.Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional programSplicing speckles are not reservoirs of RNA polymerase II, but contain an inactive form, phosphorylated on serine2 residues of the C-terminal domain.Deconvolution of chromatin immunoprecipitation-microarray (ChIP-chip) analysis of MBF occupancies reveals the temporal recruitment of Rep2 at the MBF target genesHyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator.
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C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 26 March 2004
@en
vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
C-terminal repeat domain kinas ...... e II C-terminal domain repeats
@en
C-terminal repeat domain kinas ...... II C-terminal domain repeats.
@nl
type
label
C-terminal repeat domain kinas ...... e II C-terminal domain repeats
@en
C-terminal repeat domain kinas ...... II C-terminal domain repeats.
@nl
prefLabel
C-terminal repeat domain kinas ...... e II C-terminal domain repeats
@en
C-terminal repeat domain kinas ...... II C-terminal domain repeats.
@nl
P2093
P2860
P921
P356
P1476
C-terminal repeat domain kinas ...... e II C-terminal domain repeats
@en
P2093
Arno L Greenleaf
Hemali P Phatnani
Janice C Jones
S Munir Alam
Timothy A Haystead
P2860
P304
24957-24964
P356
10.1074/JBC.M402218200
P407
P577
2004-03-26T00:00:00Z