A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
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Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseRoles of the NF-kappaB pathway in lymphocyte development and function.Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in miceIn vivo knockdown of TAK1 accelerates bone marrow proliferation/differentiation and induces systemic inflammationIn vitro studies on the antimicrobial peptide human beta-defensin 9 (HBD9): signalling pathways and pathogen-related response (an American Ophthalmological Society thesis).An essential role for TAK1 in the contact hypersensitivity responseTGFβ activated kinase 1 (TAK1) at the crossroad of B cell receptor and Toll-like receptor 9 signaling pathways in human B cells.Transforming growth factor beta-activated kinase 1 (TAK1)-dependent checkpoint in the survival of dendritic cells promotes immune homeostasis and function.TAK1 inhibition prevents the development of autoimmune diabetes in NOD mice.Isolation, semisynthesis, covalent docking and transforming growth factor beta-activated kinase 1 (TAK1)-inhibitory activities of (5Z)-7-oxozeaenol analoguesTAK1 is essential for osteoclast differentiation and is an important modulator of cell death by apoptosis and necroptosis.CARMA1- and MyD88-dependent activation of Jun/ATF-type AP-1 complexes is a hallmark of ABC diffuse large B-cell lymphomas.TAK1 deficiency in dendritic cells inhibits adaptive immunity in SRBC-immunized C57BL/6 miceTAK1 negatively regulates NF-κB and p38 MAP kinase activation in Gr-1+CD11b+ neutrophilsCritical role of B cell lymphoma 10 in BAFF-regulated NF-κB activation and survival of anergic B cells.Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination.Activation of TAK1 by MYD88 L265P drives malignant B-cell Growth in non-Hodgkin lymphoma.Torilin Inhibits Inflammation by Limiting TAK1-Mediated MAP Kinase and NF-κB ActivationRegulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer.Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update.TAK1, more than just innate immunity.Agammaglobulinemia: causative mutations and their implications for novel therapies.TAK1 regulates hepatic cell survival and carcinogenesis.TAK1 selective inhibition: state of the art and future opportunities.Roles of the NF-κB Pathway in B-Lymphocyte Biology.Transforming growth factor β activated kinase 1: a potential therapeutic target for rheumatic diseases.Essential role of TAK1 in regulating mantle cell lymphoma survival.Network Analysis of the Systemic Response to Fasciola hepatica Infection in Sheep Reveals Changes in Fibrosis, Apoptosis, Toll-Like Receptors 3/4, and B Cell Function.Analyzing synergistic and non-synergistic interactions in signalling pathways using Boolean Nested Effect Models.Negative role of TAK1 in marginal zone B-cell development incidental to NF-κB noncanonical pathway activation.Recombinant mouse prion protein alone or in combination with lipopolysaccharide alters expression of innate immunity genes in the colon of mice.TIPE2 (Tumor Necrosis Factor α-induced Protein 8-like 2) Is a Novel Negative Regulator of TAK1 Signal.PLCγ-dependent mTOR signalling controls IL-7-mediated early B cell development.TAK1 adaptor proteins, TAB2 and TAB3, link the signalosome to B-cell receptor-induced IKK activation.TAK1 maintains the survival of immunoglobulin λ-chain-positive B cells.Structure-guided development of covalent TAK1 inhibitors.Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke.The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 ComplexReovirus infection induces stabilization and up-regulation of cellular transcripts that encode regulators of TGF-β signaling
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A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 05 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
@en
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
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type
label
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
@en
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
@nl
prefLabel
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
@en
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation.
@nl
P2093
P2860
P1433
P1476
A critical role of TAK1 in B-cell receptor-mediated nuclear factor kappaB activation
@en
P2093
Andrew Podd
Demin Wang
Hong-Hsing Liu
James Schuman
Renren Wen
Yuhong Chen
Zhijian J Chen
P2860
P304
P356
10.1182/BLOOD-2008-08-176057
P407
P577
2009-02-05T00:00:00Z