Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
about
LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms.Arrhythmogenesis in Timothy Syndrome is associated with defects in Ca(2+)-dependent inactivationSimilar molecular determinants on Rem mediate two distinct modes of inhibition of CaV1.2 channels.Localized force application reveals mechanically sensitive domains of Piezo1.Engineering prokaryotic channels for control of mammalian tissue excitabilityIon channel engineering: perspectives and strategies.Split-inteins and their bioapplications.Rad and Rem are non-canonical G-proteins with respect to the regulatory role of guanine nucleotide binding in Ca(V)1.2 channel regulation.Efficient generation of bispecific IgG antibodies by split intein mediated protein trans-splicing system.Atomic mutagenesis in ion channels with engineered stoichiometrySculpting ion channel functional expression with engineered ubiquitin ligases.Pediatric Dilated Cardiomyopathy-Associated LRRC10 (Leucine-Rich Repeat-Containing 10) Variant Reveals LRRC10 as an Auxiliary Subunit of Cardiac L-Type Ca2+ Channels.
P2860
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P2860
Manipulating L-type calcium channels in cardiomyocytes using split-intein protein transsplicing
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 03 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Manipulating L-type calcium ch ...... t-intein protein transsplicing
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Manipulating L-type calcium ch ...... -intein protein transsplicing.
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type
label
Manipulating L-type calcium ch ...... t-intein protein transsplicing
@en
Manipulating L-type calcium ch ...... -intein protein transsplicing.
@nl
prefLabel
Manipulating L-type calcium ch ...... t-intein protein transsplicing
@en
Manipulating L-type calcium ch ...... -intein protein transsplicing.
@nl
P2093
P2860
P356
P1476
Manipulating L-type calcium ch ...... t-intein protein transsplicing
@en
P2093
Andrew R Marks
Donald D Chang
Henry M Colecraft
Prakash Subramanyam
P2860
P304
15461-15466
P356
10.1073/PNAS.1308161110
P407
P50
P577
2013-09-03T00:00:00Z