A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.
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Characterization of microsporidia-induced developmental arrest and a transmembrane leucine-rich repeat protein in Caenorhabditis elegansAntibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain ExchangedRecent advances on the use of structural biology for the design of novel envelope immunogens of HIV-1Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strainsEnvelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.In-solution virus capture assay helps deconstruct heterogeneous antibody recognition of human immunodeficiency virus type 1Rational antibody-based HIV-1 vaccine design: current approaches and future directionsBroad antiviral activity of carbohydrate-binding agents against the four serotypes of dengue virus in monocyte-derived dendritic cellsThe glycan shield of HIV is predominantly oligomannose independently of production system or viral clade.A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals.Structure-based vaccine design in HIV: blind men and the elephant?Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2009-2010.Rapid development of glycan-specific, broad, and potent anti-HIV-1 gp120 neutralizing antibodies in an R5 SIV/HIV chimeric virus infected macaqueHigh-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection.Antibodies elicited by yeast glycoproteins recognize HIV-1 virions and potently neutralize virions with high mannose N-glycans.Potential of carbohydrate-binding agents as therapeutics against enveloped viruses.Toward automated oligosaccharide synthesis.Structural insights into key sites of vulnerability on HIV-1 Env and influenza HA.Bitter-sweet symphony: glycan-lectin interactions in virus biology.Yeast-elicited cross-reactive antibodies to HIV Env glycans efficiently neutralize virions expressing exclusively high-mannose N-linked glycans.Conference report: "Functional Glycomics in HIV Type 1 Vaccine Design" workshop report, Bethesda, Maryland, April 30-May 1, 2012.Display of the HIV envelope protein at the yeast cell surface for immunogen development
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A yeast glycoprotein shows high-affinity binding to the broadly neutralizing human immunodeficiency virus antibody 2G12 and inhibits gp120 interactions with 2G12 and DC-SIGN.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 04 March 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
@en
A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
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type
label
A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
@en
A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
@nl
prefLabel
A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
@en
A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
@nl
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A yeast glycoprotein shows hig ...... actions with 2G12 and DC-SIGN.
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Caroline Agrawal-Gamse
Fang-Hua Lee
Innocent Mboudjeka
Lai-Xi Wang
Robert J Luallen
Robert W Doms
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P304
P356
10.1128/JVI.02537-08
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P577
2009-03-04T00:00:00Z