Selective P2X(7) receptor antagonists for chronic inflammation and pain
about
Purinergic Receptors: Key Mediators of HIV-1 Infection and InflammationPurinergic signaling in inflammatory cells: P2 receptor expression, functional effects, and modulation of inflammatory responsesP2X ion channel receptors and inflammationIn pursuit of P2X3 antagonists: novel therapeutics for chronic pain and afferent sensitization.Purinergic receptor functionality is necessary for infection of human hepatocytes by hepatitis delta virus and hepatitis B virus.Neuronal P2X7 receptor-induced reactive oxygen species production contributes to nociceptive behavior in miceThe purinergic receptor P2X7 triggers alpha-secretase-dependent processing of the amyloid precursor proteinHaplotypes of P2RX7 gene polymorphisms are associated with both cold pain sensitivity and analgesic effect of fentanyl.IL-1β and IL-18: inflammatory markers or mediators of hypertension?Estrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection.P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica.Transcriptional control mechanisms associated with the nucleotide receptor P2X7, a critical regulator of immunologic, osteogenic, and neurologic functions.Effects of genetic variation in the P2RX7 gene on pharmacodynamics of a P2X(7) receptor antagonist: a prospective genotyping approachRecent patents on novel P2X(7) receptor antagonists and their potential for reducing central nervous system inflammation.P2X purinergic receptor ligands: recently patented compounds.Emerging role of extracellular nucleotides and adenosine in multiple sclerosis.Perspectives of purinergic signaling in stem cell differentiation and tissue regeneration.Physiological roles and potential therapeutic applications of the P2X7 receptor in inflammation and pain.P2X and P2Y receptors—role in the pathophysiology of the nervous system.Central sensitization of nociceptive neurons in rat medullary dorsal horn involves purinergic P2X7 receptors.The inflammasome and danger molecule signaling: at the crossroads of inflammation and pathogen persistence in the oral cavity.Acupuncture-Induced Analgesia: A Neurobiological Basis in Purinergic Signaling.Challenges to develop novel anti-inflammatory and analgesic drugs.Natural compounds with P2X7 receptor-modulating properties.Quantitative structure-activity relationship study of P2X7 receptor inhibitors using combination of principal component analysis and artificial intelligence methods.The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types.A potential role for P2X7R in allergic airway inflammation in mice and humans.Astrocyte-neuron interaction in the substantia gelatinosa of the spinal cord dorsal horn via P2X7 receptor-mediated release of glutamate and reactive oxygen species.Salidroside Ameliorates Diabetic Neuropathic Pain in Rats by Inhibiting Neuroinflammation.Identification and characterization of related substances in EVT-401 by hyphenated LC-MS techniques.Nanobodies that block gating of the P2X7 ion channel ameliorate inflammation.Expression of P2X7 ATP receptor mediating the IL8 and CCL20 release in human periodontal ligament stem cells.Decrease of serum adenine nucleotide hydrolysis in an irritant contact dermatitis mice model: potential P2X7R involvement
P2860
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P2860
Selective P2X(7) receptor antagonists for chronic inflammation and pain
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 June 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Selective P2X
@nl
Selective P2X(7) receptor antagonists for chronic inflammation and pain
@en
type
label
Selective P2X
@nl
Selective P2X(7) receptor antagonists for chronic inflammation and pain
@en
prefLabel
Selective P2X
@nl
Selective P2X(7) receptor antagonists for chronic inflammation and pain
@en
P2093
P2860
P1476
Selective P2X(7) receptor antagonists for chronic inflammation and pain
@en
P2093
Diana Donnelly-Roberts
Michael F Jarvis
William A Carroll
P2860
P2888
P356
10.1007/S11302-008-9110-6
P577
2008-06-21T00:00:00Z