Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F(X)6LL motif in export from the endoplasmic reticulum
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Rab26 modulates the cell surface transport of α2-adrenergic receptors from the GolgiCNIH4 interacts with newly synthesized GPCR and controls their export from the endoplasmic reticulumOlfactory Receptors in Non-Chemosensory Organs: The Nervous System in Health and DiseaseA conserved motif in the membrane proximal C-terminal tail of human muscarinic m1 acetylcholine receptors affects plasma membrane expression.Systematic and quantitative analysis of G protein-coupled receptor trafficking motifs.ADP-ribosylation factors modulate the cell surface transport of G protein-coupled receptorsA single conserved leucine residue on the first intracellular loop regulates ER export of G protein-coupled receptors.Rab8 interacts with distinct motifs in alpha2B- and beta2-adrenergic receptors and differentially modulates their transport.Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties.C-terminal di-leucine motif of dopamine D₁ receptor plays an important role in its plasma membrane trafficking.A single lys residue on the first intracellular loop modulates the endoplasmic reticulum export and cell-surface expression of α2A-adrenergic receptorThe angiotensin II type 1 receptor C-terminal Lys residues interact with tubulin and modulate receptor export traffickingThe cannabinoid type-1 receptor carboxyl-terminus, more than just a tail.Alpha2B-adrenergic receptor interaction with tubulin controls its transport from the endoplasmic reticulum to the cell surface.The B7-1 cytoplasmic tail enhances intracellular transport and mammalian cell surface display of chimeric proteins in the absence of a linear ER export motif.Di-acidic motifs in the membrane-distal C termini modulate the transport of angiotensin II receptors from the endoplasmic reticulum to the cell surface.Mutating the dileucine motif of the human beta(2)-adrenoceptor reduces the high initial rate of receptor phosphorylation by GRK without affecting postendocytic sorting.Regulation of β-adrenergic receptor trafficking and lung microvascular endothelial cell permeability by Rab5 GTPase.Anterograde trafficking of nascent α(2B)-adrenergic receptor: structural basis, roles of small GTPasesA triple arg motif mediates α(2B)-adrenergic receptor interaction with Sec24C/D and export.Evidence of the importance of the first intracellular loop of prokineticin receptor 2 in receptor function.Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.A single mutation in helix 8 enhances the angiotensin II type 1a receptor transport and signaling.Identification of endoplasmic reticulum export motifs for G protein-coupled receptorsRegulation of α2B-Adrenerigc Receptor Export Trafficking by Specific MotifsRecruitment of a cytoplasmic chaperone relay by the A2A adenosine receptor.Golgi complex-plasma membrane trafficking directed by an autonomous, tribasic Golgi export signalRegulation of β2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptorMutations in the carboxyl-terminal SEC24 binding motif of the serotonin transporter impair folding of the transporter.A membrane-proximal, C-terminal α-helix is required for plasma membrane localization and function of the G Protein-coupled receptor (GPCR) TGR5Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex.Mutation of Phe318 within the NPxxY(x)(5,6)F motif in melanin-concentrating hormone receptor 1 results in an efficient signaling activity.The role of the carboxyl terminus in folding of the serotonin transporter.Pharmacoperones for Misfolded Gonadotropin Receptors.Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson disease: novel putative chemoreceptors in the human brain.Beta2-adrenergic receptor homodimers: Role of transmembrane domain 1 and helix 8 in dimerization and cell surface expression.
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P2860
Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F(X)6LL motif in export from the endoplasmic reticulum
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 31 December 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F
@nl
Anterograde trafficking of G p ...... from the endoplasmic reticulum
@en
type
label
Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F
@nl
Anterograde trafficking of G p ...... from the endoplasmic reticulum
@en
prefLabel
Anterograde trafficking of G protein-coupled receptors: function of the C-terminal F
@nl
Anterograde trafficking of G p ...... from the endoplasmic reticulum
@en
P2093
P2860
P356
P1476
Anterograde trafficking of G p ...... from the endoplasmic reticulum
@en
P2093
Charles D Nichols
Chunmin Dong
Fuguo Zhou
Guangyu Wu
Matthew T Duvernay
Xiaoping Zhang
P2860
P304
P356
10.1124/MOL.108.051623
P577
2008-12-31T00:00:00Z