Protein methylation: a new mechanism of p53 tumor suppressor regulation.
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Crosstalk between C/EBPbeta phosphorylation, arginine methylation, and SWI/SNF/Mediator implies an indexing transcription factor codeLysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell deathCurrent chemical biology approaches to interrogate protein methyltransferasesStructure of Human SMYD2 Protein Reveals the Basis of p53 Tumor Suppressor MethylationCardiac deletion of Smyd2 is dispensable for mouse heart developmentTargeting p53 for Novel Anticancer Therapy.Histone methyltransferase SETDB1 regulates liver cancer cell growth through methylation of p53p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.Posttranslational modification of p53: cooperative integrators of functionComprehensive data-driven analysis of the impact of chemoinformatic structure on the genome-wide biological response profiles of cancer cells to 1159 drugsp53 post-translational modification: deregulated in tumorigenesisWhole-genome sequencing analysis of phenotypic heterogeneity and anticipation in Li-Fraumeni cancer predisposition syndrome.Subcellular proteomics reveals a role for nucleo-cytoplasmic trafficking at the DNA replication origin activation checkpointLoss of CARM1 is linked to reduced HuR function in replicative senescence.Protein domain-level landscape of cancer-type-specific somatic mutations.Histone modifiers in cancer: friends or foes?The dynamic stress-induced "O-GlcNAc-ome" highlights functions for O-GlcNAc in regulating DNA damage/repair and other cellular pathways.Neoangiogenesis. Assessment in Esophageal Adenocarcinomas.Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression.Molecular dynamic simulation insights into the normal state and restoration of p53 function.A novel tumor suppressor network in squamous malignanciesHistone demethylases and cancer.Small Molecule Inhibitors of Protein Arginine Methyltransferases.Hypoxic Preconditioning Inhibits Hypoxia-induced Apoptosis of Cardiac Progenitor Cells via the PI3K/Akt-DNMT1-p53 Pathway.PRMT5 is required for cell-cycle progression and p53 tumor suppressor function.Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis.Extensive post-translational modification of active and inactivated forms of endogenous p53.The multiple levels of regulation by p53 ubiquitination.Lysine-specific modifications of p53: a matter of life and death?SNF5, a core component of the SWI/SNF complex, is necessary for p53 expression and cell survival, in part through eIF4E.Cardiac glycosides inhibit p53 synthesis by a mechanism relieved by Src or MAPK inhibition.Epigenetic alterations in patients with type 2 diabetes mellitusRelationship of the expression levels of XIAP and p53 genes in hepatocellular carcinoma and the prognosis of patients.Chemical and functional aspects of posttranslational modification of proteinsCell cycle control by a methylation-phosphorylation switch.BTK blocks the inhibitory effects of MDM2 on p53 activity.Reversible LSD1 inhibition with HCI-2509 induces the p53 gene expression signature and disrupts the MYCN signature in high-risk neuroblastoma cells.Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.Multiple Arginine Residues Are Methylated in Drosophila Mre11 and Required for Survival Following Ionizing Radiation.
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Protein methylation: a new mechanism of p53 tumor suppressor regulation.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on September 2008
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@en
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@nl
type
label
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@en
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@nl
prefLabel
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@en
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@nl
P2860
P356
P1476
Protein methylation: a new mechanism of p53 tumor suppressor regulation.
@en
P2093
P2860
P304
P356
10.14670/HH-23.1143
P577
2008-09-01T00:00:00Z