BTK blocks the inhibitory effects of MDM2 on p53 activity.

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Erythropoietin Intensifies the Proapoptotic Activity of LFM-A13 in Cells and in a Mouse Model of Colorectal Cancer.BTK: a two-faced effector in cancer and tumour suppression BTK modulates p73 activity to induce apoptosis independently of p53

P2860

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P2860

BTK blocks the inhibitory effects of MDM2 on p53 activity.

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http://www.wikidata.org/entity/Q47164914

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2017 nî lūn-bûn

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2017年の論文

@ja

2017年学术文章

@wuu

2017年学术文章

@zh

2017年学术文章

@zh-cn

2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

@zh-hant

name

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@en

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@nl

type

Item

label

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@en

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@nl

prefLabel

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@en

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@nl

P1476

BTK blocks the inhibitory effects of MDM2 on p53 activity.

@en

P2093

Kong Peng Lam

http://www.w3.org/2001/XMLSchema#string

Koon-Guan Lee

http://www.w3.org/2001/XMLSchema#string

Nickolai A Barlev

http://www.w3.org/2001/XMLSchema#string

Olga Fedorova

http://www.w3.org/2001/XMLSchema#string

P2860

Bruton's tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

Regulation of p53 localization and transcription by the HECT domain E3 ligase WWP1

The 26S proteasome is a multifaceted target for anti-cancer therapies

ATM-dependent phosphorylation of Mdm2 on serine 395: role in p53 activation by DNA damage

Modes of p53 regulation

p53 and metabolism

Bruton's tyrosine kinase phosphorylates DDX41 and activates its binding of dsDNA and STING to initiate type 1 interferon response.

ATM activates p53 by regulating MDM2 oligomerization and E3 processivity

Role of p53 serine 46 in p53 target gene regulation.

Damage-mediated phosphorylation of human p53 threonine 18 through a cascade mediated by a casein 1-like kinase. Effect on Mdm2 binding.

P304

106639-106647

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.18632/ONCOTARGET.22543

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Salvador Macip

M Althubiti

Akang E Ekpenyong-Akiba

Miran Rada

P577

2017-11-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

29290977

http://www.w3.org/2001/XMLSchema#string

P932

5739762

http://www.w3.org/2001/XMLSchema#string

BTK blocks the inhibitory effects of MDM2 on p53 activity.

about

P2860

P2860

BTK blocks the inhibitory effects of MDM2 on p53 activity.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932