Predicting and understanding the stability of G-quadruplexes
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Applications of High-Throughput Sequencing for In Vitro Selection and Characterization of AptamersComputational approaches towards understanding human long non-coding RNA biologyRe-evaluation of G-quadruplex propensity with G4HunterExploring possible DNA structures in real-time polymerase kinetics using Pacific Biosciences sequencer dataG-quadruplex DNA sequences are evolutionarily conserved and associated with distinct genomic features in Saccharomyces cerevisiaeStability of telomeric G-quadruplexes.An active role for machine learning in drug developmentResolution and characterization of the structural polymorphism of a single quadruplex-forming sequence.Analysis of FMRP mRNA target datasets reveals highly associated mRNAs mediated by G-quadruplex structures formed via clustered WGGA sequencesRecQ-core of BLM unfolds telomeric G-quadruplex in the absence of ATPHow long is too long? Effects of loop size on G-quadruplex stability.A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.RPA-mediated unfolding of systematically varying G-quadruplex structures.Assessing the amount of quadruplex structures present within G₂-tract synthetic random-sequence DNA librariesMapping the sequences of potential guanine quadruplex motifs.Efficient discovery of responses of proteins to compounds using active learningG-quadruplexes: from guanine gels to chemotherapeuticsA fluorescence-based helicase assay: application to the screening of G-quadruplex ligands.Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.Populated intermediates in the thermal unfolding of the human telomeric quadruplex.Quantitative analysis and prediction of G-quadruplex forming sequences in double-stranded DNASpecialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.Identification of consensus binding sites clarifies FMRP binding determinantsStability of intramolecular quadruplexes: sequence effects in the central loop.Human telomeric G-quadruplex: thermodynamic and kinetic studies of telomeric quadruplex stability.Overview of formation of G-quadruplex structures.Structure, location and interactions of G-quadruplexes.Mutation detection in plasmid-based biopharmaceuticals.The application of DNA and RNA G-quadruplexes to therapeutic medicines.Experimental approaches to identify cellular G-quadruplex structures and functions.High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.Seven essential questions on G-quadruplexes.A practical guide to studying G-quadruplex structures using single-molecule FRET.Using hidden Markov models to investigate G-quadruplex motifs in genomic sequences.Thermodynamic characterization of human telomere quadruplex unfoldingA toolbox for predicting g-quadruplex formation and stabilityMachine learning model for sequence-driven DNA G-quadruplex formation.1H, 13C, and 15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.G4PromFinder: an algorithm for predicting transcription promoters in GC-rich bacterial genomes based on AT-rich elements and G-quadruplex motifs.Molecular mechanism of G-quadruplex unwinding helicase: sequential and repetitive unfolding of G-quadruplex by Pif1 helicase.
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Predicting and understanding the stability of G-quadruplexes
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on June 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Predicting and understanding the stability of G-quadruplexes
@en
Predicting and understanding the stability of G-quadruplexes.
@nl
type
label
Predicting and understanding the stability of G-quadruplexes
@en
Predicting and understanding the stability of G-quadruplexes.
@nl
prefLabel
Predicting and understanding the stability of G-quadruplexes
@en
Predicting and understanding the stability of G-quadruplexes.
@nl
P2093
P2860
P356
P1433
P1476
Predicting and understanding the stability of G-quadruplexes
@en
P2093
David J C MacKay
Julian Huppert Leon
Linda Payet
P2860
P304
P356
10.1093/BIOINFORMATICS/BTP210
P407
P577
2009-06-01T00:00:00Z