Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA
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A molecular score by quantitative PCR as a new prognostic tool at diagnosis for chronic lymphocytic leukemia patients.The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces apoptosis, down-regulates the CXCR4 chemokine receptor and impairs migration of chronic lymphocytic leukemia cellsClinical and biological relevance of genomic heterogeneity in chronic lymphocytic leukemia.CLL cells respond to B-Cell receptor stimulation with a microRNA/mRNA signature associated with MYC activation and cell cycle progressionZAP-70 promotes the infiltration of malignant B-lymphocytes into the bone marrow by enhancing signaling and migration after CXCR4 stimulationRegulatory network reconstruction reveals genes with prognostic value for chronic lymphocytic leukemia.AMD3100 disrupts the cross-talk between chronic lymphocytic leukemia cells and a mesenchymal stromal or nurse-like cell-based microenvironment: pre-clinical evidence for its association with chronic lymphocytic leukemia treatments.Quantitative detection of zeta-chain-associated protein 70 expression in chronic lymphocytic leukemiaFcR-like 2 Inhibition of B cell receptor-mediated activation of B cells.Chronic lymphocytic leukemia microenvironment: shifting the balance from apoptosis to proliferation.An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia.Extracellular vesicles of bone marrow stromal cells rescue chronic lymphocytic leukemia B cells from apoptosis, enhance their migration and induce gene expression modifications.The role of G protein-coupled receptors in lymphoid malignancies.ZAP70 expression directly promotes chronic lymphocytic leukaemia cell adhesion to bone marrow stromal cells.
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Gene expression profiling reveals differences in microenvironment interaction between patients with chronic lymphocytic leukemia expressing high versus low ZAP70 mRNA
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 18 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Gene expression profiling reve ...... ing high versus low ZAP70 mRNA
@en
Gene expression profiling reve ...... ng high versus low ZAP70 mRNA.
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type
label
Gene expression profiling reve ...... ing high versus low ZAP70 mRNA
@en
Gene expression profiling reve ...... ng high versus low ZAP70 mRNA.
@nl
prefLabel
Gene expression profiling reve ...... ing high versus low ZAP70 mRNA
@en
Gene expression profiling reve ...... ng high versus low ZAP70 mRNA.
@nl
P2093
P2860
P1433
P1476
Gene expression profiling reve ...... ing high versus low ZAP70 mRNA
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P2093
Anne Sorée
Basile Stamatopoulos
Carole Equeter
Cécile De Bruyn
Delphine Hanosset
Dominique Bron
Laurence Lagneaux
Nathalie Meuleman
Philippe Martiat
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P304
P356
10.3324/HAEMATOL.2008.002626
P577
2009-04-18T00:00:00Z