Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay. - Wikidata - wikimedia - TriplyDB

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.

Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.

http://www.wikidata.org/entity/Q37207905

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Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact Mechanism and regulation of the nonsense-mediated decay pathway Retroviral strategy to stabilize viral RNA The Clothes Make the mRNA: Past and Present Trends in mRNP Fashion Selection for reduced translation costs at the intronic 5' end in fungi Nonsense-mediated mRNA decay in humans at a glance Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story Organizing principles of mammalian nonsense-mediated mRNA decay Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms HIV-1 Recruits UPF1 but Excludes UPF2 to Promote Nucleocytoplasmic Export of the Genomic RNA.Human Upf1 is a highly processive RNA helicase and translocase with RNP remodelling activities RNA sequencing of synaptic and cytoplasmic Upf1-bound transcripts supports contribution of nonsense-mediated decay to epileptogenesis.Modulation of nonsense mediated decay by rapamycin Experimental and Computational Considerations in the Study of RNA-Binding Protein-RNA Interactions Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae.A post-translational regulatory switch on UPF1 controls targeted mRNA degradation Human nonsense-mediated RNA decay initiates widely by endonucleolysis and targets snoRNA host genes.Detained introns are a novel, widespread class of post-transcriptionally spliced introns.Identification of elements in human long 3' UTRs that inhibit nonsense-mediated decay.The unfolded protein response is shaped by the NMD pathway NMD: At the crossroads between translation termination and ribosome recycling.Nonsense-mediated RNA decay--a switch and dial for regulating gene expression A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.Chromatoid Body Protein TDRD6 Supports Long 3' UTR Triggered Nonsense Mediated mRNA Decay.UPF2-Dependent Nonsense-Mediated mRNA Decay Pathway Is Essential for Spermatogenesis by Selectively Eliminating Longer 3'UTR Transcripts.The role of nucleotide composition in premature termination codon recognition.Identification of novel post-transcriptional features in olfactory receptor family mRNAs.A system for coordinated analysis of translational readthrough and nonsense-mediated mRNA decay.Identification of targets of tumor suppressor microRNA-34a using a reporter library system Target Discrimination in Nonsense-Mediated mRNA Decay Requires Upf1 ATPase Activity Recent transcriptome-wide mapping of UPF1 binding sites reveals evidence for its recruitment to mRNA before translation.Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway.Human nonsense-mediated mRNA decay factor UPF2 interacts directly with eRF3 and the SURF complex Upstream ORFs are prevalent translational repressors in vertebrates.Viral Evasion and Manipulation of Host RNA Quality Control Pathways.ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons.Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6- and SMG7-mediated degradation pathways.In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila.Rbfox2 controls autoregulation in RNA-binding protein networks.Regulation of natural mRNAs by the nonsense-mediated mRNA decay pathway.

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Global analyses of UPF1 binding and function reveal expanded scope of nonsense-mediated mRNA decay.

http://www.wikidata.org/entity/Q37207905

description

article científic

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article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 13 June 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@en

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@nl

type

label

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@en

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@nl

prefLabel

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@en

Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

@nl

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Global analyses of UPF1 bindin ...... nonsense-mediated mRNA decay.

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Alex D Robertson

http://www.w3.org/2001/XMLSchema#string

Christopher B Burge

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Jessica A Hurt

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P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Characterization of the biochemical properties of the human Upf1 gene product that is involved in nonsense-mediated mRNA decay.

Human SMG-1, a novel phosphatidylinositol 3-kinase-related protein kinase, associates with components of the mRNA surveillance complex and is involved in the regulation of nonsense-mediated mRNA decay

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus

Upf1 ATPase-dependent mRNP disassembly is required for completion of nonsense- mediated mRNA decay

A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling.

MicroRNA targeting specificity in mammals: determinants beyond seed pairing

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scholarly article

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10.1101/GR.157354.113

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10

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23

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2013-06-13T00:00:00Z

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23766421

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3787261

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