A coordinated network of transporters with overlapping specificities provides a robust survival strategy.
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Efflux-mediated drug resistance in bacteria: an updateAnalyzing conformational changes in the transport cycle of EmrEFunctional rotation of the transporter AcrB: insights into drug extrusion from simulationsMetal-induced conformational changes in ZneB suggest an active role of membrane fusion proteins in efflux resistance systemsThe ins and outs of RND efflux pumps in Escherichia coliSingle-step selection of drug resistant Acinetobacter baylyi ADP1 mutants reveals a functional redundancy in the recruitment of multidrug efflux systemsA Transporter Interactome Is Essential for the Acquisition of Antimicrobial Resistance to AntibioticsDynamic interplay of multidrug transporters with TolC for isoprenol tolerance in Escherichia coliA data-driven approach to modeling the tripartite structure of multidrug resistance efflux pumps.Homologs of the Acinetobacter baumannii AceI transporter represent a new family of bacterial multidrug efflux systems.Microbial efflux systems and inhibitors: approaches to drug discovery and the challenge of clinical implementationOuter membrane protein OmpW participates with small multidrug resistance protein member EmrE in quaternary cationic compound effluxInference of sparse combinatorial-control networks from gene-expression data: a message passing approach.Recruitment of genes and enzymes conferring resistance to the nonnatural toxin bromoacetate.Topologically random insertion of EmrE supports a pathway for evolution of inverted repeats in ion-coupled transportersMechanism of recognition of compounds of diverse structures by the multidrug efflux pump AcrB of Escherichia coli.A requirement of TolC and MDR efflux pumps for acid adaptation and GadAB induction in Escherichia coli.RcnB is a periplasmic protein essential for maintaining intracellular Ni and Co concentrations in Escherichia coli.Structure and mechanism of RND-type multidrug efflux pumpsA putative ABC transporter, hatABCDE, is among molecular determinants of pyomelanin production in Pseudomonas aeruginosa.Transforming a drug/H+ antiporter into a polyamine importer by a single mutation.A single-component multidrug transporter of the major facilitator superfamily is part of a network that protects Escherichia coli from bile salt stress.Functionally important carboxyls in a bacterial homologue of the vesicular monoamine transporter (VMAT).Adaptive mechanisms of Campylobacter jejuni to erythromycin treatmentThe challenge of efflux-mediated antibiotic resistance in Gram-negative bacteria.An ace up their sleeve: a transcriptomic approach exposes the AceI efflux protein of Acinetobacter baumannii and reveals the drug efflux potential hidden in many microbial pathogens.Escherichia coli YqjA, a Member of the Conserved DedA/Tvp38 Membrane Protein Family, Is a Putative Osmosensing Transporter Required for Growth at Alkaline pH.Perplexing new insight into the dynamics of the EmrE transporter.Conserved small protein associates with the multidrug efflux pump AcrB and differentially affects antibiotic resistanceSmall multidrug resistance protein EmrE reduces host pH and osmotic tolerance to metabolic quaternary cation osmoprotectants.Physical enrichment of transposon mutants from saturation mutant libraries using the TraDISort approach.New substrates on the block: clinically relevant resistances for EmrE and homologues.Tripartite assembly of RND multidrug efflux pumps.Permeability Barrier of Gram-Negative Cell Envelopes and Approaches To Bypass It.Structure and pH-induced structural rearrangements of the putative multidrug efflux pump EmrD in liposomes probed by site-directed spin labeling.Breaking the Permeability Barrier of Escherichia coli by Controlled Hyperporination of the Outer Membrane.Members of the conserved DedA family are likely membrane transporters and are required for drug resistance in Escherichia coli.Strategies for bypassing the membrane barrier in multidrug resistant Gram-negative bacteria.Broad-specificity efflux pumps and their role in multidrug resistance of Gram-negative bacteria.Understanding efflux in Gram-negative bacteria: opportunities for drug discovery.
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A coordinated network of transporters with overlapping specificities provides a robust survival strategy.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 18 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A coordinated network of trans ...... es a robust survival strategy.
@en
A coordinated network of trans ...... es a robust survival strategy.
@nl
type
label
A coordinated network of trans ...... es a robust survival strategy.
@en
A coordinated network of trans ...... es a robust survival strategy.
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prefLabel
A coordinated network of trans ...... es a robust survival strategy.
@en
A coordinated network of trans ...... es a robust survival strategy.
@nl
P2860
P356
P1476
A coordinated network of trans ...... des a robust survival strategy
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P2093
P2860
P304
P356
10.1073/PNAS.0902400106
P407
P577
2009-05-18T00:00:00Z