Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis. - Wikidata - wikimedia - TriplyDB

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

http://www.wikidata.org/entity/Q37217463

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The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) i CD14, a key candidate gene associated with a specific immune response to cockroach The rheumatoid arthritis HLA-DRB1 shared epitope.PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.Autoimmunity to peptidyl arginine deiminase type 4 precedes clinical onset of rheumatoid arthritis.Autocitrullination of human peptidyl arginine deiminase type 4 regulates protein citrullination during cell activation.Polymorphisms in the sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) gene are associated with susceptibility to asthma.Potential of ayurgenomics approach in complex trait research: leads from a pilot study on rheumatoid arthritis Insights from populations at risk for the future development of classified rheumatoid arthritis PADI4 and HLA-DRB1 are genetic risks for radiographic progression in RA patients, independent of ACPA status: results from the IORRA cohort study.High throughput proteomic analysis of the secretome in an explant model of articular cartilage inflammation PADI2 is significantly associated with rheumatoid arthritis.The lung may play a role in the pathogenesis of rheumatoid arthritis.Peptidylarginine deiminase 2, 3 and 4 have distinct specificities against cellular substrates: novel insights into autoantigen selection in rheumatoid arthritis Smoking, Porphyromonas gingivalis and the immune response to citrullinated autoantigens before the clinical onset of rheumatoid arthritis in a Southern European nested case-control study P2X7 receptor-mediated TG2 externalization: a link to inflammatory arthritis?Association of circulating adiponectin levels with progression of radiographic joint destruction in rheumatoid arthritis.Retinal deimination and PAD2 levels in retinas from donors with age-related macular degeneration (AMD).Erosive rheumatoid arthritis is associated with antibodies that activate PAD4 by increasing calcium sensitivity Rheumatoid arthritis and smoking: putting the pieces together A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22 Association of anti-peptidyl arginine deiminase antibodies with radiographic severity of rheumatoid arthritis in African Americans.Adiponectin is a mediator of the inverse association of adiposity with radiographic damage in rheumatoid arthritis.Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis.Prevalence of anti-peptidylarginine deiminase type 4 antibodies in rheumatoid arthritis and unaffected first-degree relatives in indigenous North American Populations.Increased autophagy in fibroblast-like synoviocytes leads to immune enhancement potential in rheumatoid arthritis.Autopathogenic correlation of periodontitis and rheumatoid arthritis.Pre-rheumatoid arthritis: predisposition and transition to clinical synovitis.The pathogenic potential of autoreactive antibodies in rheumatoid arthritis.Epigenetic-based immune intervention for rheumatic diseases.Proteolysis by Granzyme B Enhances Presentation of Autoantigenic Peptidylarginine Deiminase 4 Epitopes in Rheumatoid Arthritis.Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.Reliable and cost-effective serodiagnosis of rheumatoid arthritis.Transcriptomic Segregation of Human Autoantigens Useful for the Diagnosis of Autoimmune Diseases.Antibodies to native and citrullinated RA33 (hnRNP A2/B1) challenge citrullination as the inciting principle underlying loss of tolerance in rheumatoid arthritis.Anti-PAD4 autoantibodies in rheumatoid arthritis: levels in serum over time and impact on PAD4 activity as measured with a small synthetic substrate.Meta-analysis: diagnostic accuracy of antibody against peptidylarginine deiminase 4 by ELISA for rheumatoid arthritis.Comparative analysis of autoantibodies targeting peptidylarginine deiminase type 4, mutated citrullinated vimentin and cyclic citrullinated peptides in rheumatoid arthritis: associations with cytokine profiles, clinical and genetic features.Smoking is not linked to the development of anti-peptidylarginine deiminase 4 autoantibodies in rheumatoid arthritis.Citrullination as a plausible link to periodontitis, rheumatoid arthritis, atherosclerosis and Alzheimer’s disease.

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Association of autoimmunity to peptidyl arginine deiminase type 4 with genotype and disease severity in rheumatoid arthritis.

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bilimsel makale

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scientific article published on July 2008

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Association of autoimmunity to ...... erity in rheumatoid arthritis.

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Arthritis and Rheumatism

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Association of autoimmunity to ...... verity in rheumatoid arthritis

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Antony Rosen

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Audrey V Grant

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Gordon K Lam

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Joan M Bathon

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Jon T Giles

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Kathleen C Barnes

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Livia Casciola-Rosen

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Michelle L Harris

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Peisong Gao

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William W Scott

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P2860

Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case-control study

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value

Antibodies to citrullinated proteins and differences in clinical progression of rheumatoid arthritis

A New Statistical Method for Haplotype Reconstruction from Population Data

The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis

Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

PAD, a growing family of citrullinating enzymes: genes, features and involvement in disease

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1958-1967

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10.1002/ART.23596

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7

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58

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Susan J. Bartlett

Hani El-Gabalawy

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2008-07-01T00:00:00Z

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5278577

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18576335

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2692635

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