Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.
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Identifying model error in metabolic flux analysis - a generalized least squares approach.Evaluation of piggyBac-mediated CHO pools to enable material generation to support GLP toxicology studies.The 'Omics Revolution in CHO Biology: Roadmap to Improved CHO Productivity.Regulation of miR-29b-1/a transcription and identification of target mRNAs in CHO-K1 cells.Genetic analysis of heterogeneous sub-clones in recombinant Chinese hamster ovary cells.Beating the odds: The poisson distribution of all input cells during limiting dilution grossly underestimates whether a cell line is clonally-derived or not.Probing the Importance of Clonality: Single Cell Subcloning of Clonally-Derived CHO Cell Lines Yields Widely Diverse Clones Differing in Growth, Productivity and Product Quality.Accelerating patient access to novel biologics using stable pool-derived product for non-clinical studies and single clone-derived product for clinical studies.CHO-Omics Review: The Impact of Current and Emerging Technologies on Chinese Hamster Ovary Based Bioproduction.Enhanced Genome Editing Tools For Multi-Gene Deletion Knock-Out Approaches Using Paired CRISPR sgRNAs in CHO Cells.Correlation Between Expression of Recombinant Proteins and Abundance of H3K4Me3 on the Enhancer of Human Cytomegalovirus Major Immediate-Early Promoter.Karyotype variation of CHO host cell lines over time in culture characterized by chromosome counting and chromosome painting.Comparison of whole-genome bisulfite sequencing library preparation strategies identifies sources of biases affecting DNA methylation data.A reference genome of the Chinese hamster based on a hybrid assembly strategyCharacterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line
P2860
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P2860
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 12 April 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Comprehensive genome and epige ...... onary pressures and over time.
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Comprehensive genome and epige ...... onary pressures and over time.
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type
label
Comprehensive genome and epige ...... onary pressures and over time.
@en
Comprehensive genome and epige ...... onary pressures and over time.
@nl
altLabel
Comprehensive genome and epige ...... ionary pressures and over time
@en
prefLabel
Comprehensive genome and epige ...... onary pressures and over time.
@en
Comprehensive genome and epige ...... onary pressures and over time.
@nl
P2093
P2860
P50
P356
P1476
Comprehensive genome and epige ...... ionary pressures and over time
@en
P2093
Christoph Fischer
Inmaculada Hernández
Martina Baumann
Matthias Farlik
Michael Hanscho
Michael Schuster
Norbert Auer
Peter M Krempl
P2860
P304
P356
10.1002/BIT.25990
P407
P50
P577
2016-04-29T00:00:00Z