The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
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Regulation of adipocyte autophagy--the potential anti-obesity mechanism of high density lipoprotein and ApolipoproteinA-ICardioprotective functions of HDLsThe unsolved mystery of apoA-I recycling in adipocyteLoss of menin mediated by endothelial cells treated with CoPP is associated with increased maturation of adipocytesEpoxyeicosatrienoic acid agonist rescues the metabolic syndrome phenotype of HO-2-null miceHO-1 expression increases mesenchymal stem cell-derived osteoblasts but decreases adipocyte lineage.Translational Significance of Heme Oxygenase in Obesity and Metabolic SyndromeHO-1 Upregulation Attenuates Adipocyte Dysfunction, Obesity, and Isoprostane Levels in Mice Fed High Fructose Diets.Epoxyeicosatrienoic acid agonist regulates human mesenchymal stem cell-derived adipocytes through activation of HO-1-pAKT signaling and a decrease in PPARγApolipoprotein A-I mimetic peptides prevent atherosclerosis development and reduce plaque inflammation in a murine model of diabetes.Apolipoprotein A-I (apoA-I) and apoA-I mimetic peptides inhibit tumor development in a mouse model of ovarian cancerCYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.Adipocyte heme oxygenase-1 induction attenuates metabolic syndrome in both male and female obese mice.High density lipoprotein: it's not just about lipid transport anymoreL-4F differentially alters plasma levels of oxidized fatty acids resulting in more anti-inflammatory HDL in miceApolipoprotein mimetic peptides: Mechanisms of action as anti-atherogenic agents.Chronic HO-1 induction with cobalt protoporphyrin (CoPP) treatment increases oxygen consumption, activity, heat production and lowers body weight in obese melanocortin-4 receptor-deficient mice.Apolipoprotein A-I mimetic peptide L-4F prevents myocardial and coronary dysfunction in diabetic mice.Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet.High fat diet enhances cardiac abnormalities in SHR rats: Protective role of heme oxygenase-adiponectin axis.Epoxyeicosatrienoic acids and heme oxygenase-1 interaction attenuates diabetes and metabolic syndrome complicationsReciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice.Oxidative stress and heme oxygenase-1 regulated human mesenchymal stem cells differentiationApoA1: mimetic peptide reverses adipocyte dysfunction in vivo and in vitro via an increase in heme oxygenase (HO-1) and Wnt10b.Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway.ApoA-1 mimetic restores adiponectin expression and insulin sensitivity independent of changes in body weight in female obese mice.Heme oxygenase, a novel target for the treatment of hypertension and obesity?Dietary Aloe QDM Complex Reduces Obesity-Induced Insulin Resistance and Adipogenesis in Obese Mice Fed a High-Fat DietHeme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet.Uric Acid-Induced Adipocyte Dysfunction Is Attenuated by HO-1 Upregulation: Potential Role of Antioxidant Therapy to Target Obesity.Dysfunctional high-density lipoprotein and the potential of apolipoprotein A-1 mimetic peptides to normalize the composition and function of lipoproteinsDiscoidal HDL and apoA-I-derived peptides improve glucose uptake in skeletal muscle.Key regulators of mitochondrial biogenesis are increased in kidneys of growth hormone receptor knockout (GHRKO) mice.Increased heme-oxygenase 1 expression in mesenchymal stem cell-derived adipocytes decreases differentiation and lipid accumulation via upregulation of the canonical Wnt signaling cascade.Heme oxygenase (HO-1) rescue of adipocyte dysfunction in HO-2 deficient mice via recruitment of epoxyeicosatrienoic acids (EETs) and adiponectinApolipoprotein A-1 mimetic D-4F enhances isoflurane-induced eNOS signaling and cardioprotection during acute hyperglycemia.Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial FunctionIncreased HO-1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21.HDL as a biomarker, potential therapeutic target, and therapyHeme oxygenase: the key to renal function regulation.
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The L-4F mimetic peptide prevents insulin resistance through increased levels of HO-1, pAMPK, and pAKT in obese mice
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 17 February 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice
@en
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice.
@nl
type
label
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice
@en
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice.
@nl
prefLabel
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice
@en
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice.
@nl
P2093
P2860
P50
P1476
The L-4F mimetic peptide preve ...... pAMPK, and pAKT in obese mice
@en
P2093
Antonio L'Abbate
Claudia Kusmic
Dong Hyun Kim
Francesco Piccolomini
Nader G Abraham
Nitin Puri
Stephen J Peterson
P2860
P304
P356
10.1194/JLR.M800610-JLR200
P577
2009-02-17T00:00:00Z