Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress.
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BRAT1 deficiency causes increased glucose metabolism and mitochondrial malfunctionGestational diabetes is characterized by reduced mitochondrial protein expression and altered calcium signaling proteins in skeletal muscleMitochondria and cancerActivation of Akt is essential for the propagation of mitochondrial respiratory stress signaling and activation of the transcriptional coactivator heterogeneous ribonucleoprotein A2Mitochondrial retrograde signaling regulates neuronal functionSilencing of IkBβ mRNA causes disruption of mitochondrial retrograde signaling and suppression of tumor growth in vivo.Mitochondrial retrograde signaling induces epithelial-mesenchymal transition and generates breast cancer stem cells.Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.Heterogeneous nuclear ribonucleoprotein A2 is a common transcriptional coactivator in the nuclear transcription response to mitochondrial respiratory stress.Mutations in mitochondrial DNA polymerase-gamma promote breast tumorigenesisImplications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.Calcineurin/nuclear factor-κB signaling mediates isoflurane-induced hippocampal neuroinflammation and subsequent cognitive impairment in aged rats.Regulation of calcium signaling in lung cancer.Drug discovery based on genetic and metabolic findings in schizophrenia.Disruption of cytochrome c oxidase function induces the Warburg effect and metabolic reprogramming.HnRNPA2 is a novel histone acetyltransferase that mediates mitochondrial stress-induced nuclear gene expression.Mitochondrial determinants of cancer health disparities.Glycolysis inhibition by 2-deoxy-D-glucose reverts the metastatic phenotype in vitro and in vivo.Role of calcineurin, hnRNPA2 and Akt in mitochondrial respiratory stress-mediated transcription activation of nuclear gene targets.Targeting the insulin-like growth factor-1 receptor by picropodophyllin as a treatment option for glioblastoma.Mitochondrial stress-induced p53 attenuates HIF-1α activity by physical association and enhanced ubiquitination.Hypoxia-mediated mitochondrial stress in RAW264.7 cells induces osteoclast-like TRAP-positive cells.Defects in cytochrome c oxidase expression induce a metabolic shift to glycolysis and carcinogenesis.Mitochondrial quality control: Cell-type-dependent responses to pathological mutant mitochondrial DNAA distinctive physiological role for IkappaBbeta in the propagation of mitochondrial respiratory stress signaling.Enhanced osteoclastogenesis by mitochondrial retrograde signaling through transcriptional activation of the cathepsin K geneGene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA.Elucidating the Metabolic Plasticity of Cancer: Mitochondrial Reprogramming and Hybrid Metabolic States.Succinate dehydrogenase-deficient GISTs are characterized by IGF1R overexpression.
P2860
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P2860
Activation of a novel calcineurin-mediated insulin-like growth factor-1 receptor pathway, altered metabolism, and tumor cell invasion in cells subjected to mitochondrial respiratory stress.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 March 2007
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Activation of a novel calcineu ...... ochondrial respiratory stress.
@en
Activation of a novel calcineu ...... ochondrial respiratory stress.
@nl
type
label
Activation of a novel calcineu ...... ochondrial respiratory stress.
@en
Activation of a novel calcineu ...... ochondrial respiratory stress.
@nl
prefLabel
Activation of a novel calcineu ...... ochondrial respiratory stress.
@en
Activation of a novel calcineu ...... ochondrial respiratory stress.
@nl
P2093
P2860
P356
P1476
Activation of a novel calcineu ...... ochondrial respiratory stress.
@en
P2093
Gopa Biswas
Manti Guha
Narayan G Avadhani
Satish Srinivasan
P2860
P304
14536-14546
P356
10.1074/JBC.M611693200
P407
P577
2007-03-13T00:00:00Z