Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.
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Decoding Warburg's hypothesis: tumor-related mutations in the mitochondrial respiratory chainIntracellular oxygen determined by respiration regulates localization of Ras and prenylated proteins.Changing perspective on oncometabolites: from metabolic signature of cancer to tumorigenic and immunosuppressive agentsPeroxisome proliferator-activated receptor gamma coactivator-1 alpha acts as a tumor suppressor in hepatocellular carcinoma.Mitochondrial protein-linked DNA breaks perturb mitochondrial gene transcription and trigger free radical-induced DNA damage.Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer.Generation and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging.The mitochondrial DNA 4,977-bp deletion and its implication in copy number alteration in colorectal cancer.Putative role of adipose tissue in growth and metabolism of colon cancer cells.Molecular oncology focus - is carcinogenesis a 'mitochondriopathy'?Mitochondrial genome regulates mitotic fidelity by maintaining centrosomal homeostasis.Quantitative proteomic profiling studies of pancreatic cancer stem cellsPoisoning of mitochondrial topoisomerase I by lamellarin DRole of somatic mutations in vascular disease formation.Mitochondriome and cholangiocellular carcinomaChronic kidney disease, severe arterial and arteriolar sclerosis and kidney neoplasia: on the spectrum of kidney involvement in MELAS syndromeMitochondrial haplogroups and polymorphisms reveal no association with sporadic prostate cancer in a southern European population.Mitochondrial common deletion, a potential biomarker for cancer occurrence, is selected against in cancer background: a meta-analysis of 38 studies.4-Hydroxynonenal inhibits SIRT3 via thiol-specific modification.Structural contribution of C-terminal segments of NuoL (ND5) and NuoM (ND4) subunits of complex I from Escherichia coli.Mitochondrial respiratory complex I dysfunction promotes tumorigenesis through ROS alteration and AKT activationManganese superoxide dismutase: guardian of the powerhouse.Nonsense and missense mutation of mitochondrial ND6 gene promotes cell migration and invasion in human lung adenocarcinoma.Redefining the roles of mitochondrial DNA-encoded subunits in respiratory Complex I assemblyIdentification of an mtDNA mutation hot spot in UV-induced mouse skin tumors producing altered cellular biochemistry.Mitochondrial D310 mutations in the early development of breast cancerCordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathwaysHigh Glucose Induces Down-Regulated GRIM-19 Expression to Activate STAT3 Signaling and Promote Cell Proliferation in Cell CultureElectron transfer in subunit NuoI (TYKY) of Escherichia coli NADH:quinone oxidoreductase (NDH-1).Metabolism of [U-13 C]glucose in human brain tumors in vivoThe role of mitochondrial tRNA mutations in lung cancerA case-control study of maternal blood mitochondrial DNA copy number and preeclampsia riskMitochondrial DNA Mutations in Grade II and III Glioma Cell Lines Are Associated with Significant Mitochondrial Dysfunction and Higher Oxidative StressTissue-specific implications of mitochondrial alterations in aging.Physiology and pathophysiology of mitochondrial DNA.Roles of subunit NuoK (ND4L) in the energy-transducing mechanism of Escherichia coli NDH-1 (NADH:quinone oxidoreductase).Primarily screening and analyzing ESTs differentially expressed in rats' primary liver cancerDifferential transcriptomic analysis of spontaneous lung tumors in B6C3F1 mice: comparison to human non-small cell lung cancer.Mitochondrial common deletion is elevated in blood of breast cancer patients mediated by oxidative stress.Maternal blood mitochondrial DNA copy number and placental abruption risk: results from a preliminary study.
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Implications of mitochondrial DNA mutations and mitochondrial dysfunction in tumorigenesis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Implications of mitochondrial ...... dysfunction in tumorigenesis.
@en
Implications of mitochondrial ...... dysfunction in tumorigenesis.
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type
label
Implications of mitochondrial ...... dysfunction in tumorigenesis.
@en
Implications of mitochondrial ...... dysfunction in tumorigenesis.
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prefLabel
Implications of mitochondrial ...... dysfunction in tumorigenesis.
@en
Implications of mitochondrial ...... dysfunction in tumorigenesis.
@nl
P2093
P2860
P356
P1433
P1476
Implications of mitochondrial ...... dysfunction in tumorigenesis.
@en
P2093
Jianxin Lu
Lokendra Kumar Sharma
Yidong Bai
P2860
P2888
P304
P356
10.1038/CR.2009.69
P577
2009-07-01T00:00:00Z