Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model
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The associations between Parkinson's disease and cancer: the plot thickensΑlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson's DiseaseCatecholamine autotoxicity. Implications for pharmacology and therapeutics of Parkinson disease and related disordersAdvances in Stem Cell Research- A Ray of Hope in Better Diagnosis and Prognosis in Neurodegenerative DiseasesConverging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's diseaseSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsHow compensation breaks down in Parkinson's disease: Insights from modeling of denervated striatumParkinson's disease: animal models and dopaminergic cell vulnerabilityElectrochemical Analysis of NeurotransmittersDeficient Wnt signalling triggers striatal synaptic degeneration and impaired motor behaviour in adult miceDopaminergic Neurons Exhibit an Age-Dependent Decline in Electrophysiological Parameters in the MitoPark Mouse Model of Parkinson's Disease.Identifying rare and common disease associated variants in genomic data using Parkinson's disease as a model.Blood RNA biomarkers in prodromal PARK4 and rapid eye movement sleep behavior disorder show role of complexin 1 loss for risk of Parkinson's disease.Single injection of small-molecule amyloid accelerator results in cell death of nigral dopamine neurons in miceStriatal dopamine neurotransmission: regulation of release and uptakeA vesicular sequestration to oxidative deamination shift in myocardial sympathetic nerves in Parkinson's disease.Unaltered striatal dopamine release levels in young Parkin knockout, Pink1 knockout, DJ-1 knockout and LRRK2 R1441G transgenic mice.Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0.Traumatic Brain Injury Impairs Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptor Complex Formation and Alters Synaptic Vesicle Distribution in the Hippocampus.LRRK2 BAC transgenic rats develop progressive, L-DOPA-responsive motor impairment, and deficits in dopamine circuit functionNeural ablation of the PARK10 candidate Plpp3 leads to dopaminergic transmission deficits without neurodegeneration.α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals.Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonismUp-regulation of SNCA gene expression: implications to synucleinopathiesEndogenous Leucine-Rich Repeat Kinase 2 Slows Synaptic Vesicle Recycling in Striatal Neurons.Impaired intracellular trafficking defines early Parkinson's diseaseCellular processes associated with LRRK2 function and dysfunctionThe impact of a parkinsonian lesion on dynamic striatal dopamine transmission depends on nicotinic receptor activation.Implications of DNA Methylation in Parkinson's Disease.Synaptic failure and α-synuclein.ɑ-Synuclein strains and the variable pathologies of synucleinopathies.Aminochrome Toxicity is Mediated by Inhibition of Microtubules Polymerization Through the Formation of Adducts with Tubulin.Early synaptic dysfunction in Parkinson's disease: Insights from animal models.Alpha-synuclein modulates dopamine neurotransmission.α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease.Early Degeneration of Both Dopaminergic and Serotonergic Axons - A Common Mechanism in Parkinson's Disease.Preclinical development of a vaccine against oligomeric alpha-synuclein based on virus-like particles.Animal models of α-synucleinopathy for Parkinson disease drug development.
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P2860
Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 30 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Deficits in dopaminergic trans ...... ction in a new Parkinson model
@en
Deficits in dopaminergic trans ...... tion in a new Parkinson model.
@nl
type
label
Deficits in dopaminergic trans ...... ction in a new Parkinson model
@en
Deficits in dopaminergic trans ...... tion in a new Parkinson model.
@nl
prefLabel
Deficits in dopaminergic trans ...... ction in a new Parkinson model
@en
Deficits in dopaminergic trans ...... tion in a new Parkinson model.
@nl
P2093
P2860
P50
P356
P1476
Deficits in dopaminergic trans ...... ction in a new Parkinson model
@en
P2093
Dawid Potgieter
Katharina Wagner
Laura Parkkinen
Megan J Dowie
Milena Cioroch
Olaf Ansorge
Sabina Anwar
Stephanie Janezic
Thierry Deltheil
Tonya N Taylor
P2860
P304
P356
10.1073/PNAS.1309143110
P407
P50
P577
2013-09-30T00:00:00Z