CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin.
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Netrin (UNC-6) mediates dendritic self-avoidanceUNC-6/netrin and its receptors UNC-5 and UNC-40/DCC modulate growth cone protrusion in vivo in C. elegansMIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathwaysStructural and functional studies of the Ras-associating and pleckstrin-homology domains of Grb10 and Grb14Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans.Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1.Time-lapse imaging and cell-specific expression profiling reveal dynamic branching and molecular determinants of a multi-dendritic nociceptor in C. elegans.The netrin receptor DCC focuses invadopodia-driven basement membrane transmigration in vivo.Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivo.A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching.Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus.Axon guidance: asymmetric signaling orients polarized outgrowth.The role of C. elegans Ena/VASP homolog UNC-34 in neuronal polarity and motility.The growth cone: an integrator of unique cues into refined axon guidanceThe tripartite motif protein MADD-2 functions with the receptor UNC-40 (DCC) in Netrin-mediated axon attraction and branching.The growth cone cytoskeleton in axon outgrowth and guidance.Roles for netrin signaling outside of axon guidance: a view from the wormMIG-15 and ERM-1 promote growth cone directional migration in parallel to UNC-116 and WVE-1.Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegansNetrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth ConesThe Genetics of Axon Guidance and Axon Regeneration in Caenorhabditis elegansSynaptic vesicle clustering requires a distinct MIG-10/Lamellipodin isoform and ABI-1 downstream from Netrin.A dominant mutation in mec-7/β-tubulin affects axon development and regeneration in Caenorhabditis elegans neuronsRedundant canonical and noncanonical Caenorhabditis elegans p21-activated kinase signaling governs distal tip cell migrationsCLEC-38, a transmembrane protein with C-type lectin-like domains, negatively regulates UNC-40-mediated axon outgrowth and promotes presynaptic development in Caenorhabditis elegansExperimental evidence for UNC-6 (netrin) axon guidance by stochastic fluctuations of intracellular UNC-40 (DCC) outgrowth activity.The roles of multiple UNC-40 (DCC) receptor-mediated signals in determining neuronal asymmetry induced by the UNC-6 (netrin) ligand.From guidance signals to movement: signaling molecules governing growth cone turning.MIG-10 (lamellipodin) has netrin-independent functions and is a FOS-1A transcriptional target during anchor cell invasion in C. elegans.Initiating and growing an axon.Neuronal polarity in C. elegans.Bioinformatics meets parasitology.SYD-1 Promotes Multiple Developmental Steps Leading to Neuronal Connectivity.The novel Rac effector RIN-1 regulates neuronal cell migration and axon pathfinding in C. elegans.The lin-4 microRNA targets the LIN-14 transcription factor to inhibit netrin-mediated axon attraction.ENU-3 functions in an UNC-6/netrin dependent pathway parallel to UNC-40/DCC/frazzled for outgrowth and guidance of the touch receptor neurons in C. elegans.Mind the (sr)GAP - roles of Slit-Robo GAPs in neurons, brains and beyond.The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.Distinct CED-10/Rac1 domains confer context-specific functions in development
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CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
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bilimsel makale
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scientific article published on 22 May 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@en
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@nl
type
label
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@en
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@nl
prefLabel
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@en
CED-10/Rac1 mediates axon guid ...... bution of MIG-10/lamellipodin.
@nl
P2860
P1433
P1476
CED-10/Rac1 mediates axon guid ...... ibution of MIG-10/lamellipodin
@en
P2093
Christopher C Quinn
Douglas S Pfeil
P2860
P304
P356
10.1016/J.CUB.2008.04.050
P407
P577
2008-05-22T00:00:00Z