Molecular medicine of microRNAs: structure, function and implications for diabetes.
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Systematic comparison of microarray profiling, real-time PCR, and next-generation sequencing technologies for measuring differential microRNA expressionMicroRNAs in Diabetic Kidney DiseaseMicroRNAs: a new ray of hope for diabetes mellitusThe induction of microRNA targeting IRS-1 is involved in the development of insulin resistance under conditions of mitochondrial dysfunction in hepatocytes.Data for differentially expressed microRNAs in saturated fatty acid palmitate-treated HepG2 cellsReductions in laminin beta2 mRNA translation are responsible for impaired IGFBP-5-mediated mesangial cell migration in the presence of high glucose.MicroRNAs profiling in murine models of acute and chronic asthma: a relationship with mRNAs targets.Stem cells as a therapeutic target for diabetes.MicroRNA-195 promotes apoptosis in mouse podocytes via enhanced caspase activity driven by BCL2 insufficiency.Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.Identification of microRNAs expressed highly in pancreatic islet-like cell clusters differentiated from human embryonic stem cells.Integrating microRNAs into a system biology approach to acute lung injuryG-DOC: a systems medicine platform for personalized oncologyTargeting microRNAs in obesity.Next generation sequencing for profiling expression of miRNAs: technical progress and applications in drug developmentInduction of miR-96 by Dietary Saturated Fatty Acids Exacerbates Hepatic Insulin Resistance through the Suppression of INSR and IRS-1.Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism.MicroRNAs and their role in progressive kidney diseases.MicroRNAs in cholangiociliopathiesMicroRNA expression analysis in the liver of high fat diet-induced obese micePlatelet microRNAs: From platelet biology to possible disease biomarkers and therapeutic targets.microRNAs in Diabetic Kidney Disease.miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors.Decrease of microRNA-122 causes hepatic insulin resistance by inducing protein tyrosine phosphatase 1B, which is reversed by licorice flavonoid.MicroRNA-191, acting via the IRS-1/Akt signaling pathway, is involved in the hepatic insulin resistance induced by cigarette smoke extract.Data on the decreased expression of FOXO1 by miR-1271 in HepG2 hepatocytes.Data on the expression and insulin-stimulated phosphorylation of IRS-1 by miR-96 in L6-GLUT4myc myocytes.Data on the expression of PEPCK in HepG2 hepatocytes transfected with miR-195.Data on the effect of miR-15b on the expression of INSR in murine C2C12 myocytes.Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study.Obesity-induced miR-15b is linked causally to the development of insulin resistance through the repression of the insulin receptor in hepatocytes.
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P2860
Molecular medicine of microRNAs: structure, function and implications for diabetes.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 15 August 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@en
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@nl
type
label
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@en
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@nl
prefLabel
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@en
Molecular medicine of microRNAs: structure, function and implications for diabetes.
@nl
P2860
P1476
Molecular medicine of microRNAs: structure, function and implications for diabetes
@en
P2093
Erica Hennessy
P2860
P356
10.1017/S1462399408000781
P577
2008-08-15T00:00:00Z