Olfactory behavior and physiology are disrupted in prion protein knockout mice
about
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo.Involvement of PrP(C) in kainate-induced excitotoxicity in several mouse strains.Regulation of GABA(A) and glutamate receptor expression, synaptic facilitation and long-term potentiation in the hippocampus of prion mutant miceNCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?Knockout of the prion protein (PrP)-like Sprn gene does not produce embryonic lethality in combination with PrP(C)-deficiencyFunctions of the cellular prion protein, the end of Moore's law, and Ockham's razor theoryFishing for prion protein functionAblation of mouse adult neurogenesis alters olfactory bulb structure and olfactory fear conditioning.N-glycans and glycosylphosphatidylinositol-anchor act on polarized sorting of mouse PrP(C) in Madin-Darby canine kidney cells.To develop with or without the prion protein.Review: contribution of transgenic models to understanding human prion disease.Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesionAmyloid beta inhibits olfactory bulb activity and the ability to smellEffect of IP3R3 and NPY on age-related declines in olfactory stem cell proliferation.Identification of novel putative-binding proteins for cellular prion protein and a specific interaction with the STIP1 homology and U-Box-containing protein 1.Prion protein at the crossroads of physiology and disease.An endocannabinoid system is present in the mouse olfactory epithelium but does not modulate olfaction.Expression of the Prion Protein Family Member Shadoo Causes Drug Hypersensitivity That Is Diminished by the Coexpression of the Wild Type Prion Protein.Olfactory dysfunction: common in later life and early warning of neurodegenerative disease.Prion protein and its role in signal transduction.Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress.Activating transcription factor 5 is required for mouse olfactory bulb development via interneuron.Dual role of cellular prion protein in normal host and Alzheimer's disease.Implications of peptide assemblies in amyloid diseases.Prion-like disorders: blurring the divide between transmissibility and infectivity.Elucidating the function of the prion protein.Uncontrolled SFK-mediated protein trafficking in prion and Alzheimer's diseaseBehavioral abnormalities in prion protein knockout mice and the potential relevance of PrP(C) for the cytoskeleton.Common themes in PrP signaling: the Src remains the same.The cellular prion protein promotes olfactory sensory neuron survival and axon targeting during adult neurogenesis.
P2860
Q27301257-5420CB28-F069-4BD8-A11D-08EC3FA942E4Q27308826-5DBAF07C-1168-4158-A6BF-05213D408E7BQ27337373-849EFA0B-B6FC-4853-B9F6-AC20E2787264Q28071519-2C1D7DCC-F73C-4C4E-9BAB-6833B4EEDD3FQ28509844-0E382513-DC51-497A-A7F5-9B0A47264637Q28597985-0164BB1A-2FBE-45D3-AA6F-E873DE1B9223Q33425420-32FDADE0-7DE6-4D14-97EF-4629ECED3786Q33806423-6C619AB2-09D4-4A42-8C1B-A05ACD0F1327Q34023780-5C25EDD0-BE7B-45AD-93AE-032C398F7D5AQ34391248-33B72158-7B67-4BF5-A761-F3195D2661A2Q34474868-1227A162-26E4-4A55-AEB2-54F1FC8172F7Q34922583-673B97EB-00D5-4F78-AA64-5B050B005BBBQ35005939-115779D6-18A4-4E44-AEC0-299B86F03E21Q35044392-3DEA8A7F-4B3E-4111-B05F-911E04E21DE2Q35735220-9A8EF1F6-A173-4FF1-BC83-1172DDBC6220Q35740063-15CEB017-E294-4C3A-B692-E884DD74EB9AQ35798292-E48D3F82-C69C-474D-80F9-DFBB2AE242EEQ36744507-26B00F38-CEC6-4B72-A015-61B6D4E4CF46Q38085616-03E51856-5282-4FE9-B6D2-8A97EA9DA98FQ38088184-E6B31BCE-3094-447C-923D-0ADF49700047Q38215344-D209F938-D11D-4CF9-B4E6-8EB7770920EDQ38300905-655D5ED5-92AA-4110-9C17-17AF7E890020Q39245173-FC674B71-B095-4B0D-86C3-378A224F1BA9Q39431937-485115DD-5A74-45E4-84AB-BD471515A6E1Q39863503-381D21C8-686C-4831-BC59-3066BDAFB6F4Q41576509-CD11F6DF-2072-4D9C-96F1-99E8C475B82BQ41717128-59B91D49-4D17-484F-8474-6118EA38A5F2Q41852101-88487CAA-8287-45FD-9507-72444F307554Q41910140-30763C03-E67D-4574-9132-CF2483D8AE3AQ52631854-452E2D06-564B-44E3-9744-8CD86D85B1BB
P2860
Olfactory behavior and physiology are disrupted in prion protein knockout mice
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 21 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Olfactory behavior and physiology are disrupted in prion protein knockout mice
@en
Olfactory behavior and physiology are disrupted in prion protein knockout mice.
@nl
type
label
Olfactory behavior and physiology are disrupted in prion protein knockout mice
@en
Olfactory behavior and physiology are disrupted in prion protein knockout mice.
@nl
prefLabel
Olfactory behavior and physiology are disrupted in prion protein knockout mice
@en
Olfactory behavior and physiology are disrupted in prion protein knockout mice.
@nl
P2093
P2860
P50
P356
P1433
P1476
Olfactory behavior and physiology are disrupted in prion protein knockout mice
@en
P2093
Alexander T Chesler
Claire E Le Pichon
Magdalini Polymenidou
Stuart Firestein
P2860
P2888
P356
10.1038/NN.2238
P407
P577
2008-12-21T00:00:00Z
P5875
P6179
1034867646