Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence. - Wikidata - wikimedia - TriplyDB

Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.

Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.

http://www.wikidata.org/entity/Q37247728

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Yeast: a simple model system to study complex phenomena of aneuploidy Cryptococcus gattii infections Aneuploidy and drug resistance in pathogenic fungi Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomes Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans Fluconazole alters the polysaccharide capsule of Cryptococcus gattii and leads to distinct behaviors in murine Cryptococcosis Gene Function Analysis in the Ubiquitous Human Commensal and Pathogen Malassezia Genus Fungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.Multilocus sequence typing of serially collected isolates of Cryptococcus from HIV-infected patients in South Africa.Mismatch Repair of DNA Replication Errors Contributes to Microevolution in the Pathogenic Fungus Cryptococcus neoformans Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata High-dose fluconazole in combination with amphotericin B is more efficient than monotherapy in murine model of cryptococcosis.Heteroresistance of Cryptococcus gattii to fluconazole.Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs.Regulatory circuitry governing fungal development, drug resistance, and disease.Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity Correlation of anti-fungal susceptibility with clinical outcomes in patients with cryptococcal meningitis.Cryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistance Identification of a Cryptococcus neoformans cytochrome P450 lanosterol 14α-demethylase (Erg11) residue critical for differential susceptibility between fluconazole/voriconazole and itraconazole/posaconazole.Involvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans.Heteroresistance to Itraconazole Alters the Morphology and Increases the Virulence of Cryptococcus gattii.Clinical significance of the isolation of Candida species from hospitalized patients.Cryptococcus neoformans Yop1 , an endoplasmic reticulum curvature-stabilizing protein, participates with Sey1 in influencing fluconazole-induced disomy formation Abdominal Lymphonodular Cryptococcosis in an Immunocompetent Child Fluconazole Susceptibility in Cryptococcus gattii Is Dependent on the ABC Transporter Pdr11.Retrospective Study of Cryptococcal Meningitis With Elevated Minimum Inhibitory Concentration to Fluconazole in Immunocompromised Patients.Identification of QTLs Associated with Virulence Related Traits and Drug Resistance in Cryptococcus neoformans.Cryptococcus: from environmental saprophyte to global pathogen.Azole heteroresistance in Cryptococcus neoformans: emergence of resistant clones with chromosomal disomy in the mouse brain during fluconazole treatment Balancing stability and flexibility within the genome of the pathogen Cryptococcus neoformans.Mechanisms of cryptococcal virulence and persistence.Fluconazole resistance in cryptococcal disease: emerging or intrinsic?Cryptococcosis: epidemiology, fungal resistance, and new alternatives for treatment.Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.Activity of VT-1129 against Cryptococcus neoformans clinical isolates with high fluconazole MICs.Molecular characterisation and antifungal susceptibility of clinical Cryptococcus deuterogattii (AFLP6/VGII) isolates from Southern Brazil.

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P2860

Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.

http://www.wikidata.org/entity/Q37247728

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 04 May 2009

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Heteroresistance to fluconazol ...... and associated with virulence.

@en

Heteroresistance to fluconazol ...... and associated with virulence.

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type

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Heteroresistance to fluconazol ...... and associated with virulence.

@en

Heteroresistance to fluconazol ...... and associated with virulence.

@nl

prefLabel

Heteroresistance to fluconazol ...... and associated with virulence.

@en

Heteroresistance to fluconazol ...... and associated with virulence.

@nl

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Antimicrobial Agents and Chemotherapy

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Heteroresistance to fluconazol ...... and associated with virulence.

@en

P2093

Edward Sionov

http://www.w3.org/2001/XMLSchema#string

H Martin Garraffo

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Kyung J Kwon-Chung

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Yun C Chang

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P2860

The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans

Genetic architecture of Hsp90-dependent drug resistance.

Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole.

Rapid, transient fluconazole resistance in Candida albicans is associated with increased mRNA levels of CDR.

Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages.

Heteroresistance to fluconazole and voriconazole in Cryptococcus neoformans.

Correlation of fluconazole MICs with clinical outcome in cryptococcal infection

Dynamic and heterogeneous mutations to fluconazole resistance in Cryptococcus neoformans.

Trends in antifungal drug susceptibility of Cryptococcus neoformans isolates in the United States: 1992 to 1994 and 1996 to 1998.

Hsp90 potentiates the rapid evolution of new traits: drug resistance in diverse fungi.

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2804-2815

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scholarly article

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10.1128/AAC.00295-09

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7

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ATP-binding cassette transporter

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