Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole.
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Cryptococcus gattii infectionsCryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomesCharacterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformansTranscriptome Profile of the Response of Paracoccidioides spp. to a Camphene Thiosemicarbazide DerivativeHigh-Resolution Genetics Identifies the Lipid Transfer Protein Sec14p as Target for Antifungal ErgolinesAntifungal Therapy: New Advances in the Understanding and Treatment of MycosisFungal cytochrome P450 sterol 14α-demethylase (CYP51) and azole resistance in plant and human pathogens.Iron regulation of the major virulence factors in the AIDS-associated pathogen Cryptococcus neoformans.Efflux in fungi: la pièce de résistancePhylogenetic analysis of fungal ABC transporters.Fungal PDR transporters: Phylogeny, topology, motifs and function.Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis.Cryptococcus neoformans resistance to echinocandins: (1,3)beta-glucan synthase activity is sensitive to echinocandins.Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype ARegulatory circuitry governing fungal development, drug resistance, and disease.Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformans.Elucidating drug resistance in human fungal pathogens.Drug strategies targeting CYP51 in neglected tropical diseasesDifferential gene expression in auristatin PHE-treated Cryptococcus neoformansInvolvement of PDK1, PKC and TOR signalling pathways in basal fluconazole tolerance in Cryptococcus neoformans.Copy number variation contributes to cryptic genetic variation in outbreak lineages of Cryptococcus gattii from the North American Pacific Northwest.Cryptococcus neoformans Yop1 , an endoplasmic reticulum curvature-stabilizing protein, participates with Sey1 in influencing fluconazole-induced disomy formationCryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for fluconazole, itraconazole, posaconazole, and voriconazole.Mutations define cross-talk between the N-terminal nucleotide-binding domain and transmembrane helix-2 of the yeast multidrug transporter Pdr5: possible conservation of a signaling interface for coupling ATP hydrolysis to drug transportStress, drugs, and evolution: the role of cellular signaling in fungal drug resistanceEfflux-mediated antifungal drug resistance.Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulence.Cryptococcus: from environmental saprophyte to global pathogen.Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor.The Cryptococcus neoformans transcriptome at the site of human meningitis.Mechanisms of cryptococcal virulence and persistence.Yeast ABC proteins involved in multidrug resistance.Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates.Medically important fungi respond to azole drugs: an update.The fungal resistome: a risk and an opportunity for the development of novel antifungal therapies.A subdose of fluconazole alters the virulence of Cryptococcus gattii during murine cryptococcosis and modulates type I interferon expression.Identification and properties of plasma membrane azole efflux pumps from the pathogenic fungi Cryptococcus gattii and Cryptococcus neoformans.G484S amino acid substitution in lanosterol 14-alpha demethylase (ERG11) is related to fluconazole resistance in a recurrent Cryptococcus neoformans clinical isolate.In vivo development of fluconazole resistance in serial Cryptococcus gattii isolates from a cat.Membrane fluidity and lipid composition of fluconazole resistant and susceptible strains of Candida albicans isolated from diabetic patients.
P2860
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P2860
Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazole.
description
2003 nî lūn-bûn
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2003 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2003 թվականի հունվարին հրատարակված գիտական հոդված
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2003年の論文
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2003年学术文章
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2003年学术文章
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2003年学术文章
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2003年学术文章
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name
Identification and characteriz ...... the resistance to fluconazole.
@ast
Identification and characteriz ...... the resistance to fluconazole.
@en
type
label
Identification and characteriz ...... the resistance to fluconazole.
@ast
Identification and characteriz ...... the resistance to fluconazole.
@en
prefLabel
Identification and characteriz ...... the resistance to fluconazole.
@ast
Identification and characteriz ...... the resistance to fluconazole.
@en
P2093
P2860
P50
P1476
Identification and characteriz ...... the resistance to fluconazole.
@en
P2093
Giovanni Fadda
Lucio Romano
Marilena La Sorda
Stefania Boccia
P2860
P304
P356
10.1046/J.1365-2958.2003.03281.X
P407
P577
2003-01-01T00:00:00Z