Sertoli cell Dicer is essential for spermatogenesis in mice. - Wikidata - wikimedia - TriplyDB

Sertoli cell Dicer is essential for spermatogenesis in mice.

Sertoli cell Dicer is essential for spermatogenesis in mice.

http://www.wikidata.org/entity/Q37250562

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Loss of Dicer in Sertoli cells has a major impact on the testicular proteome of mice Epigenetics: A key paradigm in reproductive health Cell-specific ablation in the testis: what have we learned?Extracellular microRNAs from the epididymis as potential mediators of cell-to-cell communication Regulatory non-coding transcripts in spermatogenesis: shedding light on 'dark matter'Dicer1 depletion in male germ cells leads to infertility due to cumulative meiotic and spermiogenic defects Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development GATA4 regulates Sertoli cell function and fertility in adult male mice Insulin receptor substrate 2 is required for testicular development Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice The mitochondrial genome encodes abundant small noncoding RNAs Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.Androgen-responsive microRNAs in mouse Sertoli cells.The microRNA-processing enzyme dicer maintains juxtaglomerular cells Constitutive WNT/beta-catenin signaling in murine Sertoli cells disrupts their differentiation and ability to support spermatogenesis Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary.The roles of microRNAs in regulation of mammalian spermatogenesis Research resource: the dynamic transcriptional profile of sertoli cells during the progression of spermatogenesis.An essential role for insulin and IGF1 receptors in regulating sertoli cell proliferation, testis size, and FSH action in mice Expression profiling reveals developmentally regulated lncRNA repertoire in the mouse male germline Male germ cell apoptosis: regulation and biology.Testicular postgenomics: targeting the regulation of spermatogenesis.MicroRNAs dynamically remodel gastrointestinal smooth muscle cells Dicer is required for haploid male germ cell differentiation in mice.A multi-faceted approach to understanding male infertility: gene mutations, molecular defects and assisted reproductive techniques (ART).Germ cell-specific targeting of DICER or DGCR8 reveals a novel role for endo-siRNAs in the progression of mammalian spermatogenesis and male fertility.Role of microRNAs in controlling gene expression in different segments of the human epididymis Misexpression of testicular microRNA in sterile Xenopus hybrids points to tetrapod-specific microRNAs associated with male fertility.Sex-biased miRNA expression in Atlantic halibut (Hippoglossus hippoglossus) brain and gonads.Integrating microRNAs into the complexity of gonadotropin signaling networks Computer-assisted annotation of murine Sertoli cell small RNA transcriptome.Expression of miRNAs in ovine fetal gonads: potential role in gonadal differentiation.Dicer ablation impairs prostate stem cell activity and causes prostate atrophy.A novel class of somatic small RNAs similar to germ cell pachytene PIWI-interacting small RNAs.Environmentally induced epigenetic transgenerational inheritance of male infertility.Detection and quantitative analysis of small RNAs by PCR Minireview: The roles of small RNA pathways in reproductive medicine Murine follicular development requires oocyte DICER, but not DROSHA.The role of Dicer1 in the male reproductive tract.Embryonic stem cell miRNAs and their roles in development and disease.

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Sertoli cell Dicer is essential for spermatogenesis in mice.

http://www.wikidata.org/entity/Q37250562

description

2008 nî lūn-bûn

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Sertoli cell Dicer is essential for spermatogenesis in mice.

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Sertoli cell Dicer is essential for spermatogenesis in mice.

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type

label

Sertoli cell Dicer is essential for spermatogenesis in mice.

@en

Sertoli cell Dicer is essential for spermatogenesis in mice.

@nl

prefLabel

Sertoli cell Dicer is essential for spermatogenesis in mice.

@en

Sertoli cell Dicer is essential for spermatogenesis in mice.

@nl

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J.YDBIO.2008.11.011

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Developmental Biology

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Sertoli cell Dicer is essential for spermatogenesis in mice.

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Bernard Jégou

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Brian D Harfe

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Chanjae Park

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Charles E Vejnar

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Evgeny M Zdobnov

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Florence Aubry

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Florian Guillou

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Francoise Kühne

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Jean-Luc Pitetti

http://www.w3.org/2001/XMLSchema#string

Marilena D Papaioannou

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P2860

The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb.

Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure

The impact of microRNAs on protein output

Widespread changes in protein synthesis induced by microRNAs

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis

Dicer function is essential for lung epithelium morphogenesis.

Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

The role of site accessibility in microRNA target recognition

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250-259

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scholarly article

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10.1016/J.YDBIO.2008.11.011

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1

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326

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Michael McManus

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2008-11-28T00:00:00Z

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23652010

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19071104

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2705812

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