SirT1 is an inhibitor of proliferation and tumor formation in colon cancer - Wikidata - wikimedia - TriplyDB

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

http://www.wikidata.org/entity/Q37258577

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SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stability Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation Bioactive Compounds Isolated from Microalgae in Chronic Inflammation and Cancer Diverse roles of SIRT1 in cancer biology and lipid metabolism Resveratrol inhibits protein translation in hepatic cells Energy sensing pathways: Bridging type 2 diabetes and colorectal cancer?SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells.Histone/protein deacetylase SIRT1 is an anticancer therapeutic target.Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.Sirt1 and cell migration.Histones: Controlling Tumor Signaling Circuitry Activating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression.The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.Sorting out functions of sirtuins in cancer Sirtuin 1 facilitates chemoresistance of pancreatic cancer cells by regulating adaptive response to chemotherapy-induced stress Down-regulation of mir-221 and mir-222 restrain prostate cancer cell proliferation and migration that is partly mediated by activation of SIRT1.Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cells Histone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase.SIRT1 inhibits the mouse intestinal motility and epithelial proliferation.Prognostic and clinical value of Sirt1 expression in gastric cancer: A systematic meta-analysis.Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer.Sirtuin regulation in aging and injury Are sirtuins viable targets for improving healthspan and lifespan?Janus-faced role of SIRT1 in tumorigenesis.Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in man Autophagy in Ischemic Livers: A Critical Role of Sirtuin 1/Mitofusin 2 Axis in Autophagy Induction.SIRT1: recent lessons from mouse models.SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer.SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.The emerging and diverse roles of sirtuins in cancer: a clinical perspective.p30 DBC is a potential regulator of tumorigenesis.SIRT1 promotes metastasis of human osteosarcoma cells.Circadian clock circuitry in colorectal cancer.New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin.Sirtuin 1 (SIRT1): the misunderstood HDAC.Sirtuin activators and inhibitors.Sirtuins and cancer: new insights and cell signaling.Inflammatory pathways in the early steps of colorectal cancer development.

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SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

http://www.wikidata.org/entity/Q37258577

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 11 May 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

@en

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.

@nl

type

label

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

@en

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.

@nl

prefLabel

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

@en

SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.

@nl

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P356

JBC.M109.000034

P1433

Journal of Biological Chemistry

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SirT1 is an inhibitor of proliferation and tumor formation in colon cancer

@en

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Baozong Li

http://www.w3.org/2001/XMLSchema#string

Chuangui Wang

http://www.w3.org/2001/XMLSchema#string

Domenico Coppola

http://www.w3.org/2001/XMLSchema#string

Jiandong Chen

http://www.w3.org/2001/XMLSchema#string

Lihong Chen

http://www.w3.org/2001/XMLSchema#string

Neha Kabra

http://www.w3.org/2001/XMLSchema#string

Timothy Yeatman

http://www.w3.org/2001/XMLSchema#string

Xiaohong Zhang

http://www.w3.org/2001/XMLSchema#string

Zhenyu Li

http://www.w3.org/2001/XMLSchema#string

P2860

Negative control of p53 by Sir2alpha promotes cell survival under stress

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

Phosphorylation of HuR by Chk2 regulates SIRT1 expression

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

SIRT1 regulates the function of the Nijmegen breakage syndrome protein

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

P304

18210-18217

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scholarly article

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10.1074/JBC.M109.000034

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27

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284

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2009-05-11T00:00:00Z

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19433578

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2709385

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