SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
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SIRT1 promotes N-Myc oncogenesis through a positive feedback loop involving the effects of MKP3 and ERK on N-Myc protein stabilityRegulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum CDeacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradationBioactive Compounds Isolated from Microalgae in Chronic Inflammation and CancerDiverse roles of SIRT1 in cancer biology and lipid metabolismResveratrol inhibits protein translation in hepatic cellsEnergy sensing pathways: Bridging type 2 diabetes and colorectal cancer?SIRT1 is necessary for proficient telomere elongation and genomic stability of induced pluripotent stem cells.Histone/protein deacetylase SIRT1 is an anticancer therapeutic target.Loss of Sirt1 function improves intestinal anti-bacterial defense and protects from colitis-induced colorectal cancer.Sirt1 and cell migration.Histones: Controlling Tumor Signaling CircuitryActivating transcription factor 4 confers a multidrug resistance phenotype to gastric cancer cells through transactivation of SIRT1 expression.The Expression of SIRT1 and DBC1 in Laryngeal and Hypopharyngeal Carcinomas.Sorting out functions of sirtuins in cancerSirtuin 1 facilitates chemoresistance of pancreatic cancer cells by regulating adaptive response to chemotherapy-induced stressDown-regulation of mir-221 and mir-222 restrain prostate cancer cell proliferation and migration that is partly mediated by activation of SIRT1.Preclinical evaluation of a novel SIRT1 modulator SRT1720 in multiple myeloma cellsHistone deacetylase SIRT1 modulates and deacetylates DNA base excision repair enzyme thymine DNA glycosylase.SIRT1 inhibits the mouse intestinal motility and epithelial proliferation.Prognostic and clinical value of Sirt1 expression in gastric cancer: A systematic meta-analysis.Expression of DBC1 is associated with nuclear grade and HER2 expression in breast cancer.Sirtuin regulation in aging and injuryAre sirtuins viable targets for improving healthspan and lifespan?Janus-faced role of SIRT1 in tumorigenesis.Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.Pharmacokinetics and tolerability of SRT2104, a first-in-class small molecule activator of SIRT1, after single and repeated oral administration in manAutophagy in Ischemic Livers: A Critical Role of Sirtuin 1/Mitofusin 2 Axis in Autophagy Induction.SIRT1: recent lessons from mouse models.SIRT1 Expression Is Associated with Good Prognosis in Colorectal Cancer.SIRT1 is a Highly Networked Protein That Mediates the Adaptation to Chronic Physiological Stress.The emerging and diverse roles of sirtuins in cancer: a clinical perspective.p30 DBC is a potential regulator of tumorigenesis.SIRT1 promotes metastasis of human osteosarcoma cells.Circadian clock circuitry in colorectal cancer.New paradigms in chronic intestinal inflammation and colon cancer: role of melatonin.Sirtuin 1 (SIRT1): the misunderstood HDAC.Sirtuin activators and inhibitors.Sirtuins and cancer: new insights and cell signaling.Inflammatory pathways in the early steps of colorectal cancer development.
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P2860
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 May 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
@en
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.
@nl
type
label
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
@en
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.
@nl
prefLabel
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
@en
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer.
@nl
P2093
P2860
P356
P1476
SirT1 is an inhibitor of proliferation and tumor formation in colon cancer
@en
P2093
Baozong Li
Chuangui Wang
Domenico Coppola
Jiandong Chen
Lihong Chen
Neha Kabra
Timothy Yeatman
Xiaohong Zhang
P2860
P304
18210-18217
P356
10.1074/JBC.M109.000034
P407
P577
2009-05-11T00:00:00Z