Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation - Wikidata - wikimedia - TriplyDB

Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation

Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation

http://www.wikidata.org/entity/Q37258749

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The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease Origin of developmental precursors dictates the pathophysiologic role of cardiac fibroblasts Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages.RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species.Class I HDACs regulate angiotensin II-dependent cardiac fibrosis via fibroblasts and circulating fibrocytes.Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction.ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets Statins and myocardial remodelling: cell and molecular pathways.Distinct mesenchymal alterations in N-cadherin and E-cadherin positive primary renal epithelial cells Rho-kinase in development and heart failure: insights from genetic models Rho associated coiled-coil kinase-1 regulates collagen-induced phosphatidylserine exposure in platelets CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis.Tumor necrosis factor: a mechanistic link between angiotensin-II-induced cardiac inflammation and fibrosis.Rho kinase as a therapeutic target in cardiovascular disease.SHP-2 acts via ROCK to regulate the cardiac actin cytoskeleton.Mitochondrial fission triggered by hyperglycemia is mediated by ROCK1 activation in podocytes and endothelial cells Mesenchymal stem cell-derived inflammatory fibroblasts promote monocyte transition into myeloid fibroblasts via an IL-6-dependent mechanism in the aging mouse heart.Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1.Developmental basis of adult cardiovascular diseases: valvular heart diseases.Electrical and mechanical stimulation of cardiac cells and tissue constructs.ROCK1 Induces Endothelial-to-Mesenchymal Transition in Glomeruli to Aggravate Albuminuria in Diabetic Nephropathy.Fibrocytes: emerging effector cells in chronic inflammation Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease Th1/M1 conversion to th2/m2 responses in models of inflammation lacking cell death stimulates maturation of monocyte precursors to fibroblasts Phosphocholine-containing ligands direct CRP induction of M2 macrophage polarization independent of T cell polarization: Implication for chronic inflammatory states.Cell type-specific signaling function of RhoA GTPase: lessons from mouse gene targeting.The many facets of the matricelluar protein periostin during cardiac development, remodeling, and pathophysiology.Rho kinases in cardiovascular physiology and pathophysiology: the effect of fasudil.Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1.The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation.Function and fate of myofibroblasts after myocardial infarction Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts.Targeting cardiac fibroblasts to treat fibrosis of the heart: focus on HDACs.Mechanotransduction and fibrosis.Inhibition of ROCK1 kinase modulates both tumor cells and stromal fibroblasts in pancreatic cancer.Molecular networks underlying myofibroblast fate and fibrosis.Pleiotropic Effects of Statins on the Cardiovascular System.Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis.TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis

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Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation

http://www.wikidata.org/entity/Q37258749

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 30 April 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Rho kinase-1 mediates cardiac ...... precursor cell differentiation

@en

Rho kinase-1 mediates cardiac ...... recursor cell differentiation.

@nl

type

label

Rho kinase-1 mediates cardiac ...... precursor cell differentiation

@en

Rho kinase-1 mediates cardiac ...... recursor cell differentiation.

@nl

prefLabel

Rho kinase-1 mediates cardiac ...... precursor cell differentiation

@en

Rho kinase-1 mediates cardiac ...... recursor cell differentiation.

@nl

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Cardiovascular Research

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Rho kinase-1 mediates cardiac ...... precursor cell differentiation

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Damon Gupta

http://www.w3.org/2001/XMLSchema#string

JoAnn Trial

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Lei Wei

http://www.w3.org/2001/XMLSchema#string

Mark L Entman

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Oliver Dewald

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Robert J Schwartz

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Sandra B Haudek

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P2860

Rocks: multifunctional kinases in cell behaviour

Regulation and functions of Rho-associated kinase

Markers of mouse macrophage development detected by monoclonal antibodies

Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment

ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts.

Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species

Targeted disruption of the mouse rho-associated kinase 2 gene results in intrauterine growth retardation and fetal death.

Bone marrow-derived fibroblast precursors mediate ischemic cardiomyopathy in mice.

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511-518

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scholarly article

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10.1093/CVR/CVP135

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3

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83

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24393943

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19406912

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2709463

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