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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

http://www.wikidata.org/entity/Q37259407

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Current Advances in Virus-Like Particles as a Vaccination Approach against HIV Infection The role of Fc-FcγR interactions in IgG-mediated microbial neutralization Electrochemistry of nonconjugated proteins and glycoproteins. Toward sensors for biomedicine and glycomics Recent strategies targeting HIV glycans in vaccine design Structural insights on the role of antibodies in HIV-1 vaccine and therapy Novel approaches and challenges to treatment of central nervous system viral infections HIV-1 functional cure: will the dream come true?Antibody responses to envelope glycoproteins in HIV-1 infection Antibodies in HIV-1 vaccine development and therapy CD4 T-cell immunotherapy for chronic viral infections and cancer HIV broadly neutralizing antibody targets AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity Molecular evolution of broadly neutralizing Llama antibodies to the CD4-binding site of HIV-1 HIV-1 receptor binding site-directed antibodies using a VH1-2 gene segment orthologue are activated by Env trimer immunization Structural basis for HIV-1 gp120 recognition by a germ-line version of a broadly neutralizing antibody Somatic Mutations of the Immunoglobulin Framework Are Generally Required for Broad and Potent HIV-1 Neutralization Restricting HIV-1 pathways for escape using rationally designed anti–HIV-1 antibodies Heavy Chain-Only IgG2b Llama Antibody Effects Near-Pan HIV-1 Neutralization by Recognizing a CD4-Induced Epitope That Includes Elements of Coreceptor- and CD4-Binding Sites Structural Basis for Enhanced HIV-1 Neutralization by a Dimeric Immunoglobulin G Form of the Glycan-Recognizing Antibody 2G12 Antibody 8ANC195 Reveals a Site of Broad Vulnerability on the HIV-1 Envelope Spike Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers.Patterns of HIV/SIV Prevention and Control by Passive Antibody Immunization Recent Progress toward Engineering HIV-1-Specific Neutralizing Monoclonal Antibodies Using animal models to overcome temporal, spatial and combinatorial challenges in HIV persistence research HIV-1 gp120 as a therapeutic target: navigating a moving labyrinth IBC's 23rd Annual Antibody Engineering, 10th Annual Antibody Therapeutics international conferences and the 2012 Annual Meeting of The Antibody Society: December 3-6, 2012, San Diego, CA Latency reversal and viral clearance to cure HIV-1.Asymmetric recognition of HIV-1 Envelope trimer by V1V2 loop-targeting antibodies.Engineering antibody-like inhibitors to prevent and treat HIV-1 infection.High-multiplicity HIV-1 infection and neutralizing antibody evasion mediated by the macrophage-T cell virological synapse.Computational analysis of anti-HIV-1 antibody neutralization panel data to identify potential functional epitope residues Immunopathogenesis of simian immunodeficiency virus infection in nonhuman primates Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys.Early antibody therapy can induce long-lasting immunity to SHIV Which Antibody Functions are Important for an HIV Vaccine?Antibody 10-1074 suppresses viremia in HIV-1-infected individuals Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller Immunologic strategies for HIV-1 remission and eradication.Characterization of VRC01, a potent and broadly neutralizing anti-HIV mAb, produced in transiently and stably transformed tobacco.Antibody-mediated immunotherapy of macaques chronically infected with SHIV suppresses viraemia.

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

http://www.wikidata.org/entity/Q37259407

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 24 October 2012

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@en

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@nl

type

label

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@en

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@nl

prefLabel

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@en

HIV therapy by a combination of broadly neutralizing antibodies in humanized mice.

@nl

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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice

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Alexander Abadir

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Alexander Ploss

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Ariel Halper-Stromberg

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Eva Billerbeck

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Florian Klein

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Henning Gruell

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Hugo Mouquet

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Jeffrey V Ravetch

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Johannes F Scheid

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Joshua A Horwitz

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P2860

Increasing the potency and breadth of an HIV antibody by using structure-based rational design

Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9

Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Humanized mice recapitulate key features of HIV-1 infection: a novel concept using long-acting anti-retroviral drugs for treating HIV-1

Antibody neutralization and escape by HIV-1

Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target

Broad neutralization coverage of HIV by multiple highly potent antibodies

Human immunodeficiency virus type 1 env clones from acute and early subtype B infections for standardized assessments of vaccine-elicited neutralizing antibodies

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118-122

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scholarly article

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10.1038/NATURE11604

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492

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Christian Gaebler

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2012-10-24T00:00:00Z

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23103874

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