Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
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Resistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) AntibioticsIncorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus.4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide (ML267), a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth.FabH mutations confer resistance to FabF-directed antibiotics in Staphylococcus aureusHow bacterial pathogens eat host lipids: implications for the development of fatty acid synthesis therapeutics.Growth-Environment Dependent Modulation of Staphylococcus aureus Branched-Chain to Straight-Chain Fatty Acid Ratio and Incorporation of Unsaturated Fatty AcidsActivation of Exogenous Fatty Acids to Acyl-Acyl Carrier Protein Cannot Bypass FabI Inhibition in Neisseria.Efficacy and Safety of AFN-1252, the First Staphylococcus-Specific Antibacterial Agent, in the Treatment of Acute Bacterial Skin and Skin Structure Infections, Including Those in Patients with Significant ComorbiditiesEnvironmental fatty acids enable emergence of infectious Staphylococcus aureus resistant to FASII-targeted antimicrobials.The Burkholderia pseudomallei enoyl-acyl carrier protein reductase FabI1 is essential for in vivo growth and is the target of a novel chemotherapeutic with efficacy.Bacterial fatty acid metabolism in modern antibiotic discovery.Exogenous fatty acid metabolism in bacteria.Clinical Relevance of Type II Fatty Acid Synthesis Bypass in Staphylococcus aureus.Staphylococcus aureus utilizes host-derived lipoprotein particles as sources of exogenous fatty acids.Therapeutic Targets in Chlamydial Fatty Acid and Phospholipid SynthesisThe Energy-Coupling Factor Transporter Module EcfAA'T, a Novel Candidate for the Genetic Basis of Fatty Acid-Auxotrophic Small-Colony Variants of
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Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 August 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
@en
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.
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type
label
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
@en
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.
@nl
prefLabel
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
@en
Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice.
@nl
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Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice
@en
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Charles O Rock
Jason W Rosch
Joshua B Parsons
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P304
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10.1128/AAC.01038-13
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P577
2013-08-26T00:00:00Z