Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression
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Tissue- and Serum-Associated Biomarkers of Hepatocellular CarcinomaZinc finger protein 64 promotes Toll-like receptor-triggered proinflammatory and type I interferon production in macrophages by enhancing p65 subunit activationNotch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation.Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.Targeting Notch signaling pathway to overcome drug resistance for cancer therapyRole of liver stem cells in hepatocarcinogenesis.Quantification of the host response proteome after mammalian reovirus T1L infection.Novel therapeutic strategies for targeting liver cancer stem cells.Notch signaling proteins: legitimate targets for cancer therapy.A New Player in the Development of TRAIL Based Therapies for Hepatocarcinoma Treatment: ATM Kinase.Septin4_i1 regulates apoptosis in hepatic stellate cells through peroxisome proliferator-activated receptor-γ/Akt/B-cell lymphoma 2 pathway.Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms.Notch signal suppresses Toll-like receptor-triggered inflammatory responses in macrophages by inhibiting extracellular signal-regulated kinase 1/2-mediated nuclear factor κB activation.NOTCH2 signaling confers immature morphology and aggressiveness in human hepatocellular carcinoma cellsThe Histone Deacetylase Inhibitor Vaproic Acid Induces Cell Growth Arrest in Hepatocellular Carcinoma Cells via Suppressing Notch Signaling.Notch signaling is activated in human hepatocellular carcinoma and induces tumor formation in miceYes-associated protein up-regulates Jagged-1 and activates the Notch pathway in human hepatocellular carcinomaNotch signaling: targeting cancer stem cells and epithelial-to-mesenchymal transitionNovel strategies targeting cancer stem cells through phytochemicals and their analogsCancer stem cells and hepatocellular carcinomaNotch signalling in solid tumours: a little bit of everything but not all the time.Piwis and piwi-interacting RNAs in the epigenetics of cancer.Emerging signaling pathways in hepatocellular carcinoma.Hepatocellular carcinoma: targeting of oncogenic signaling networks in TRAIL resistant cancer cells.Molecular signalling in hepatocellular carcinoma: Role of and crosstalk among WNT/ß-catenin, Sonic Hedgehog, Notch and Dickkopf-1.Role of CSL-dependent and independent Notch signaling pathways in cell apoptosis.The complex role of NOTCH receptors and their ligands in the development of hepatoblastoma, cholangiocarcinoma and hepatocellular carcinoma.Inhibition of Notch1 signaling overcomes resistance to the death ligand Trail by specificity protein 1-dependent upregulation of death receptor 5.Notch4 Signaling Confers Susceptibility to TRAIL-Induced Apoptosis in Breast Cancer Cells.Notch signaling in cerebrovascular diseases (Review)Targeting Notch3 in Hepatocellular Carcinoma: Molecular Mechanisms and Therapeutic Perspectives.Impaired cell functions of hepatocytes incubated with plasma of septic patients.Notch1 differentially regulates oncogenesis by wildtype p53 overexpression and p53 mutation in grade III hepatocellular carcinoma.Hepatitis B virus X protein blunts senescence-like growth arrest of human hepatocellular carcinoma by reducing Notch1 cleavage.Inhibition of γ-secretase activity synergistically enhances tumour necrosis factor-related apoptosis-inducing ligand induced apoptosis in T-cell acute lymphoblastic leukemia cells via upregulation of death receptor 5Anti-cancer effects of curcumin on lung cancer through the inhibition of EZH2 and NOTCH1.p53 in the CNS: Perspectives on Development, Stem Cells, and Cancer.Fucose is on the TRAIL of colon cancer.Schistosoma japonicum soluble egg antigens facilitate hepatic stellate cell apoptosis by downregulating Akt expression and upregulating p53 and DR5 expression.Notch-driven carcinogenesis: the merging of hepatocellular cancer and cholangiocarcinoma into a common molecular liver cancer subtype.
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P2860
Notch1 signaling sensitizes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human hepatocellular carcinoma cells by inhibiting Akt/Hdm2-mediated p53 degradation and up-regulating p53-dependent DR5 expression
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 17 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Notch1 signaling sensitizes tu ...... g p53-dependent DR5 expression
@en
Notch1 signaling sensitizes tu ...... p53-dependent DR5 expression.
@nl
type
label
Notch1 signaling sensitizes tu ...... g p53-dependent DR5 expression
@en
Notch1 signaling sensitizes tu ...... p53-dependent DR5 expression.
@nl
prefLabel
Notch1 signaling sensitizes tu ...... g p53-dependent DR5 expression
@en
Notch1 signaling sensitizes tu ...... p53-dependent DR5 expression.
@nl
P2093
P2860
P356
P1476
Notch1 signaling sensitizes tu ...... g p53-dependent DR5 expression
@en
P2093
Chunmei Wang
Huazhang An
Qinghua Zhang
Xuetao Cao
Zhengxin Wang
P2860
P304
16183-16190
P356
10.1074/JBC.M109.002105
P407
P577
2009-04-17T00:00:00Z