about
Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cellsMolecular origins of cancer: Molecular basis of colorectal cancerTherapeutic Implications of Targeting AKT Signaling in MelanomaMutant p53 Drives Cancer by Subverting Multiple Tumor Suppression PathwaysA critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapySapacitabine for cancerKilling me softly--future challenges in apoptosis researchTherapeutic targeting of cancers with loss of PTEN function.Synthetic lethality in lung cancer and translation to clinical therapiesChemoresistance and targeted therapies in ovarian and endometrial cancersObesity and colorectal cancer: molecular features of adipose tissueTumor Suppressor Inactivation in the Pathogenesis of Adult T-Cell LeukemiaA genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replicationComputer-aided targeting of the PI3K/Akt/mTOR pathway: toxicity reduction and therapeutic opportunitiesPro-survival role for Parkinson's associated gene DJ-1 revealed in trophically impaired dopaminergic neuronsRegulation of PTEN stability and activity by Plk3Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells.High-resolution analysis of aberrant regions in autosomal chromosomes in human leukemia THP-1 cell line.Novel mechanism of tumor suppression by polarity gene discs large 1 (DLG1) revealed in a murine model of pediatric B-ALL.Plk1 protein phosphorylates phosphatase and tensin homolog (PTEN) and regulates its mitotic activity during the cell cycleLoss of phosphatase and tensin homolog expression correlates with clinicopathological features of non-small cell lung cancer patients and its impact on survival: A systematic review and meta-analysis.Association between PTEN Gene IVS4 polymorphism and risk of cancer: a meta-analysisRegional differences in gallbladder cancer pathogenesis: insights from a comparison of cell cycle-regulatory, PI3K, and pro-angiogenic protein expression.Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.Cdh1, a substrate-recruiting component of anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, specifically interacts with phosphatase and tensin homolog (PTEN) and promotes its removal from chromatin.Ribosomal DNA copy number loss and sequence variation in cancerModulation in activation and expression of phosphatase and tensin homolog on chromosome ten, Akt1, and 3-phosphoinositide-dependent kinase 1: further evidence demonstrating altered phosphoinositide 3-kinase signaling in postmortem brain of suicide sPTEN is a negative regulator of mitotic checkpoint complex during the cell cycleA genome-wide siRNA screen identifies novel phospho-enzymes affecting Wnt/β-catenin signaling in mouse embryonic stem cells.The phosphatase and tensin homologue deleted on chromosome 10 mediates radiosensitivity in head and neck cancer.Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers.HOXA10 is associated with temozolomide resistance through regulation of the homologous recombinant DNA repair pathway in glioblastoma cell lines.PTEN loss compromises homologous recombination repair in astrocytes: implications for glioblastoma therapy with temozolomide or poly(ADP-ribose) polymerase inhibitors.PINCH1 regulates Akt1 activation and enhances radioresistance by inhibiting PP1alphaPhospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome.The emerging role of pseudogene expressed non-coding RNAs in cellular functionsMuscle-specific inositide phosphatase (MIP/MTMR14) is reduced with age and its loss accelerates skeletal muscle aging process by altering calcium homeostasis.PTEN interacts with histone H1 and controls chromatin condensation.RAKing in AKT: a tumor suppressor function for the intracellular tyrosine kinase FRK.PTEN and p53 cross-regulation induced by soy isoflavone genistein promotes mammary epithelial cell cycle arrest and lobuloalveolar differentiation
P2860
Q24313224-79AAE171-688F-43BA-A364-6F70BB14F071Q24617331-F53931B8-620F-4268-99A5-252555CAA757Q24631438-71427722-7359-4DB6-A2BC-421D3E94CE83Q26767396-21C6EA82-9B2A-41A2-B92D-698E6A2ADE6BQ26849503-F8603898-1941-49A5-A65A-76FCC0064BDDQ27024675-7C0254AC-7B4F-493A-8C8D-A44A2CB6654AQ27025213-5CF85723-89DB-46EB-A907-F7443226B293Q27852764-C98F2B7F-BADB-4EBE-B24C-C5DC8F55C4F2Q28072904-9752EAA1-E53C-445F-B526-160B4FE5F407Q28073246-1266809F-BCEE-4EE0-8D1D-EBC10CC48F05Q28079556-6F9A5629-E301-466A-828E-3524D19AAF59Q28081287-9C5EDA3F-6AE9-4D10-AC91-31372E041165Q28245811-4650BDD4-543F-4396-A518-C3B44B69A68FQ28397537-4556D5FA-8B35-4BCE-9DA7-DB8CD0FD8E5EQ28473591-150792BB-08FA-4979-9A56-57E005729242Q28512686-4488654B-BA0E-4FA3-A2D2-1BF1B024A713Q32178019-787CC269-4496-41DF-B017-C5CCA82F8722Q33487434-285159EA-A98D-442C-8C7A-A3B398438C34Q33551348-FDAD42BD-BCB1-4C91-9C2B-7BD8C026BC26Q33619449-084C6804-BF62-4DB6-8E26-2052BB84B67AQ33633647-7C2115C0-101E-4CFD-BD9D-D194A8707210Q33716992-563DE8DF-164A-4028-A47A-9EF85367C358Q33721146-E9D20730-38ED-4C7A-BDD8-65D26146A5F3Q33727905-2E75B881-6E68-48E5-80CD-CF605A11E48DQ33793077-31340ED8-FF61-444C-9379-826BEFA05B15Q33825098-E1A1B733-5D2A-433F-89AF-B384B0AE6503Q33843600-C0AC43B9-DBDF-4900-9C7A-20F7EFCE92B7Q33857310-00A61C98-C3B6-4E7A-A445-AF53AE6B8750Q33873840-88F75C59-39D9-432F-AFD8-0A9DE9B91C74Q33906083-2A257BCD-0761-4F3D-A715-5ABBF689062FQ33917649-49D3E631-74F5-41B6-A480-54C8A0FF105EQ33925330-64E32BB0-483F-499D-811E-42497F161F22Q33958963-83BC8D5D-8A6B-417F-87FC-AF29CCA0F56BQ33968025-E025055B-477F-43CF-A953-255099358881Q34016649-AFC9E955-D3C3-4DC1-BB96-E62252CA9E8FQ34160931-8499293A-C79F-4247-9E1B-435154FB6DC9Q34194294-F8EA36BA-BED1-4D00-B3D0-D7697834A589Q34364654-E8CFEAE0-6246-4E17-A6CB-49258B573ADDQ34420665-92DDBC01-D715-4BC8-9AA7-DCBCE1D5B270Q34514602-F9BF934B-9880-4742-BC16-DA9CFF69BF4F
P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on September 2008
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
PTEN: a new guardian of the genome.
@en
PTEN: a new guardian of the genome.
@nl
type
label
PTEN: a new guardian of the genome.
@en
PTEN: a new guardian of the genome.
@nl
prefLabel
PTEN: a new guardian of the genome.
@en
PTEN: a new guardian of the genome.
@nl
P2860
P356
P1433
P1476
PTEN: a new guardian of the genome
@en
P2093
P2860
P2888
P304
P356
10.1038/ONC.2008.241
P407
P577
2008-09-01T00:00:00Z