Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor
about
Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines.Apigenin Inhibits Human SW620 Cell Growth by Targeting Polyamine Catabolism.Polyamine-blocking therapy reverses immunosuppression in the tumor microenvironment.Determinants of the differential antizyme-binding affinity of ornithine decarboxylaseEvidence of a role for antizyme and antizyme inhibitor as regulators of human cancer.Phase I/II clinical trial of 2-difluoromethyl-ornithine (DFMO) and a novel polyamine transport inhibitor (MQT 1426) for feline oral squamous cell carcinoma.Current status of the polyamine research fieldMammalian polyamine metabolism and functionPolyamine transport as a target for treatment of Pneumocystis pneumonia.Polyamine homoeostasis.Cancer chemoprevention locks onto a new polyamine metabolic target.Antitumor conjugates with polyamine vectors and their molecular mechanisms.Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells.Targeting polyamine metabolism for cancer therapy and prevention.AMXT-1501, a novel polyamine transport inhibitor, synergizes with DFMO in inhibiting neuroblastoma cell proliferation by targeting both ornithine decarboxylase and polyamine transport.Polyamine depletion enhances the roscovitine-induced apoptosis through the activation of mitochondria in HCT116 colon carcinoma cells.Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells.Evaluation of Polyamine Transport Inhibitors in a Drosophila Epithelial Model Suggests the Existence of Multiple Transport Systems.An overview of polyamine metabolism in pancreatic ductal adenocarcinoma.Cancer cell targeting driven by selective polyamine reactivity with glycine propargyl esters.Alpha-Difluoromethylornithine, an Irreversible Inhibitor of Polyamine Biosynthesis, as a Therapeutic Strategy against Hyperproliferative and Infectious Diseases.Modulation of biogenic amines content by poly(propylene imine) dendrimers in rats.
P2860
Q26783914-CCC21B65-21AB-41FE-8158-8CCE2B97DD14Q33720933-F200C874-AE37-4A05-98B3-3D46D3999555Q33914402-FE27959F-855A-4493-BADA-07FEEF7EFAA4Q34071636-9E6291AB-69A5-4852-A20A-5C5D4435255AQ35386279-B7203FF4-24CB-4D4D-ABF2-D86680E68264Q35580905-3C9BC546-1942-49AC-8A40-2CF31C850564Q36838564-CB839D3C-8133-412B-AFF4-25915D8802BAQ37365983-905F6F79-F0B4-43F9-B216-6B64437DBD18Q37450672-E13CBC4C-234B-47CF-BD76-11EABA2B028DQ37679972-1414C52D-8A21-41DD-AA86-BDBFBD5AEEDEQ37681944-4F570ACB-1438-48A4-BE7A-A4DE54058687Q37773362-F8BF670D-B0F5-448D-98E6-35367E035355Q38912611-3C546E67-8190-4C9E-A33F-C795AE145173Q38966691-C7C3BDC7-982E-4038-9DB4-FC54ADF54DACQ39185908-7180C521-2F03-47E0-86AB-CF9618A965A1Q39496558-E9439378-2A46-4E4F-9528-6F695AE4C7F9Q41107342-79A93254-37DB-4FD6-9DDA-EAEB858E87C4Q41347219-15C0C6D3-6FA6-46C6-9E67-681353AAFC4FQ48307540-C7BEFEC2-FDC1-4F85-9AE3-863352B074EDQ48310001-0B69F341-3C69-486B-A31F-35F06491C323Q48317030-83A720DA-433B-4162-B261-21332757924CQ48506495-F8AF46B3-1AD9-4C13-9B41-3669224414DEQ48638069-E18EF1B8-5FA8-461E-9F3F-43C42C95A289
P2860
Lipophilic lysine-spermine conjugates are potent polyamine transport inhibitors for use in combination with a polyamine biosynthesis inhibitor
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Lipophilic lysine-spermine con ...... lyamine biosynthesis inhibitor
@en
Lipophilic lysine-spermine con ...... yamine biosynthesis inhibitor.
@nl
type
label
Lipophilic lysine-spermine con ...... lyamine biosynthesis inhibitor
@en
Lipophilic lysine-spermine con ...... yamine biosynthesis inhibitor.
@nl
prefLabel
Lipophilic lysine-spermine con ...... lyamine biosynthesis inhibitor
@en
Lipophilic lysine-spermine con ...... yamine biosynthesis inhibitor.
@nl
P2093
P2860
P356
P1476
Lipophilic lysine-spermine con ...... lyamine biosynthesis inhibitor
@en
P2093
Gerard F Graminski
Mark R Burns
Reitha S Weeks
Thomas G O'Brien
P2860
P304
P356
10.1021/JM801580W
P407
P577
2009-04-01T00:00:00Z