Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs).
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NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting "stemness".Metabolic enzymes: key modulators of functionality in cancer stem-like cells.The miR-29 transcriptome in endocrine-sensitive and resistant breast cancer cells.Targeting cancer cell mitochondria as a therapeutic approach: recent updates.Mitochondrial "power" drives tamoxifen resistance: NQO1 and GCLC are new therapeutic targets in breast cancer.Mechanisms of action and therapeutic efficacies of the lipophilic antimycobacterial agents clofazimine and bedaquiline.Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.Mitochondrial dysfunction and potential anticancer therapy.Mitochondrial biomarkers predict tumor progression and poor overall survival in gastric cancers: Companion diagnostics for personalized medicine.Vitamin C and Doxycycline: A synthetic lethal combination therapy targeting metabolic flexibility in cancer stem cells (CSCs).Mitochondrial markers predict recurrence, metastasis and tamoxifen-resistance in breast cancer patients: Early detection of treatment failure with companion diagnostics.Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.Mitoketoscins: Novel mitochondrial inhibitors for targeting ketone metabolism in cancer stem cells (CSCs).Targeting flavin-containing enzymes eliminates cancer stem cells (CSCs), by inhibiting mitochondrial respiration: Vitamin B2 (Riboflavin) in cancer therapy.Exploiting mitochondrial targeting signal(s), TPP and bis-TPP, for eradicating cancer stem cells (CSCs).Mitochondrial fission as a driver of stemness in tumor cells: mDIVI1 inhibits mitochondrial function, cell migration and cancer stem cell (CSC) signalling.Cancer stem cells (CSCs): metabolic strategies for their identification and eradication.A mitochondrial based oncology platform for targeting cancer stem cells (CSCs): MITO-ONC-RXDoxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study
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Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs).
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 22 June 2016
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
@en
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
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type
label
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
@en
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
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prefLabel
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
@en
Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
@nl
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Bedaquiline, an FDA-approved a ...... stem-like cancer cells (CSCs).
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Anna Rita Cappello
Marco Fiorillo
Rebecca Lamb
Ubaldo E Martinez-Outschoorn
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P304
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10.18632/AGING.100983
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2016-06-22T00:00:00Z