Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.

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A mitochondrial based oncology platform for targeting cancer stem cells (CSCs): MITO-ONC-RX Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study

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Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.

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2017 nî lūn-bûn

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Mitochondrial mRNA transcripts ...... iagnostics for cancer therapy.

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Mitochondrial mRNA transcripts ...... iagnostics for cancer therapy.

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Mitochondrial mRNA transcripts ...... iagnostics for cancer therapy.

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Mitochondrial mRNA transcripts ...... iagnostics for cancer therapy.

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Implementing an online tool for genome-wide validation of survival-associated biomarkers in ovarian-cancer using microarray data from 1287 patients.

Telomere length and mortality following a diagnosis of ovarian cancer

Mitochondria as new therapeutic targets for eradicating cancer stem cells: Quantitative proteomics and functional validation via MCT1/2 inhibition.

Antibiotics that target mitochondria effectively eradicate cancer stem cells, across multiple tumor types: treating cancer like an infectious disease.

Doxycycline down-regulates DNA-PK and radiosensitizes tumor initiating cells: Implications for more effective radiation therapy.

Dissecting tumor metabolic heterogeneity: Telomerase and large cell size metabolically define a sub-population of stem-like, mitochondrial-rich, cancer cells

Telomere length is a prognostic biomarker in elderly advanced ovarian cancer patients: a multicenter GINECO study

High mitochondrial mass identifies a sub-population of stem-like cancer cells that are chemo-resistant.

Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs).

Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells.

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scholarly article

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10.18632/ONCOTARGET.19963

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English

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Michael P. Lisanti

Federica Sotgia

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2017-08-06T00:00:00Z

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28978006

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ovarian cancer

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5620146

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Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.

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P2860

P2860

Mitochondrial mRNA transcripts predict overall survival, tumor recurrence and progression in serous ovarian cancer: Companion diagnostics for cancer therapy.

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