The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel
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Fast- or slow-inactivated state preference of Na+ channel inhibitors: a simulation and experimental studyA molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channelExploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.Volatile anesthetics inhibit sodium channels without altering bulk lipid bilayer properties.Functional extension of amino acid triads from the fourth transmembrane segment (S4) into its external linker in Shaker K(+) channels.Gating transitions in the selectivity filter region of a sodium channel are coupled to the domain IV voltage sensor.The Biophysical Basis Underlying Gating Changes in the p.V1316A Mutant Nav1.7 Channel and the Molecular Pathogenesis of Inherited Erythromelalgia.The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating.
P2860
Q28474487-42218752-F945-4F11-9068-8DC1E274B3EAQ28579256-E52CBE26-D0AE-43A4-8B50-6027D4A27695Q30363787-AF6B4787-301A-4915-AA9A-F03E180042E4Q34566656-63FA218E-6522-4AA1-B4BC-31A8C0F25878Q35423838-14A09A3E-B5D9-40BD-A2A2-C17A0EB612CDQ35787126-098EBACB-4D30-4DB9-9E5A-00F0B5F2A02EQ36139482-C706B745-9AFB-438D-8F79-C5602D29E9B4Q37755990-DD77F373-C75F-4209-B4B9-CFC85D1F447FQ46696659-494D12B0-55CE-4DA3-B377-4DC46B541788
P2860
The external pore loop interacts with S6 and S3-S4 linker in domain 4 to assume an essential role in gating control and anticonvulsant action in the Na(+) channel
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
The external pore loop interac ...... nticonvulsant action in the Na
@nl
The external pore loop interac ...... nt action in the Na(+) channel
@en
type
label
The external pore loop interac ...... nticonvulsant action in the Na
@nl
The external pore loop interac ...... nt action in the Na(+) channel
@en
prefLabel
The external pore loop interac ...... nticonvulsant action in the Na
@nl
The external pore loop interac ...... nt action in the Na(+) channel
@en
P2093
P2860
P356
P1476
The external pore loop interac ...... nt action in the Na(+) channel
@en
P2093
Chung-Chin Kuo
Jui-Yi Hsieh
Ya-Chin Yang
P2860
P304
P356
10.1085/JGP.200810158
P577
2009-08-01T00:00:00Z