Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
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Neural stem/progenitor cells in Alzheimer's diseasec-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's DiseaseRole of pro-inflammatory cytokines released from microglia in Alzheimer's diseaseNeuroinflammation in Alzheimer's disease: chemokines produced by astrocytes and chemokine receptorsA deficiency in CCR2+ monocytes: the hidden side of Alzheimer's diseaseOxidized cholesterol as the driving force behind the development of Alzheimer's diseasePathophysiology of the neurovascular unit: disease cause or consequence?Targeting neuroinflammation in Alzheimer's diseaseFeasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-βBrain endothelial cells synthesize neurotoxic thrombin in Alzheimer's disease.Nutritional and Pharmacological Strategies to Regulate Microglial Polarization in Cognitive Aging and Alzheimer's Disease.Microarray analysis on human neuroblastoma cells exposed to aluminum, β(1-42)-amyloid or the β(1-42)-amyloid aluminum complex.Effects of collagen-induced rheumatoid arthritis on amyloidosis and microvascular pathology in APP/PS1 mice.Cerebral amyloid angiopathy impact on endothelium.Melatonin alters age-related changes in transcription factors and kinase activation.Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease.Induction of an inflammatory loop by interleukin-1β and tumor necrosis factor-α involves NF-kB and STAT-1 in differentiated human neuroprogenitor cells.Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer's diseaseAmyloidosis associated with cerebral amyloid angiopathy: cell signaling pathways elicited in cerebral endothelial cells.Blood-brain barrier transport of amyloid beta peptides in efflux pump knock-out animals evaluated by in vivo optical imaging.MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of Alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10)ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Abeta(1-40) peptides.Intravenous immunoglobulin protects neurons against amyloid beta-peptide toxicity and ischemic stroke by attenuating multiple cell death pathways.Basic mechanisms of neurodegeneration: a critical update.NETosis in Alzheimer's Disease.Targeting mitochondrial dysfunction in neurodegenerative disease: Part II.Apolipoprotein E, amyloid-beta, and neuroinflammation in Alzheimer's diseaseCitrus bergamia Juice Extract Attenuates β-Amyloid-Induced Pro-Inflammatory Activation of THP-1 Cells Through MAPK and AP-1 Pathways.Control of transferrin expression by β-amyloid through the CP2 transcription factor.The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effects.Immunotherapies in Alzheimer's disease: Too much, too little, too late or off-target?Aβ-Induced Insulin Resistance and the Effects of Insulin on the Cholesterol Synthesis Pathway and Aβ Secretion in Neural Cells.Modulation of Neuroinflammation in the Central Nervous System: Role of Chemokines and Sphingolipids.Molecular Anti-inflammatory Mechanisms of Retinoids and Carotenoids in Alzheimer's Disease: a Review of Current Evidence.Induction of GADD34 Regulates the Neurotoxicity of Amyloid β.Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model.Expression and Processing of Amyloid Precursor Protein in Vascular Endothelium.Water-soluble ginseng oligosaccharides protect against scopolamine-induced cognitive impairment by functioning as an antineuroinflammatory agent.Is there a causal link between inflammation and dementia?Role of Aβ-receptor for advanced glycation endproducts interaction in oxidative stress and cytosolic phospholipase A₂ activation in astrocytes and cerebral endothelial cells.
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Expression of inflammatory genes induced by beta-amyloid peptides in human brain endothelial cells and in Alzheimer's brain is mediated by the JNK-AP1 signaling pathway.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 31 December 2008
@en
vedecký článok
@sk
vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@en
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@nl
type
label
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@en
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@nl
prefLabel
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@en
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway.
@nl
P2093
P2860
P921
P1476
Expression of inflammatory gen ...... the JNK-AP1 signaling pathway
@en
P2093
Babette Weksler
Danica B Stanimirovic
Debbie Callaghan
Douglas Walker
Lih-Fen Lue
Pierre-Oliver Couraud
Qing Yan Liu
Vanja Vukic
P2860
P304
P356
10.1016/J.NBD.2008.12.007
P577
2008-12-31T00:00:00Z