A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease. - Wikidata - wikimedia - TriplyDB

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

http://www.wikidata.org/entity/Q37289982

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Intra-individual purifying selection on mitochondrial DNA variants during human oogenesis.Nutritional Interventions for Mitochondrial OXPHOS Deficiencies: Mechanisms and Model Systems.A dynamic invertible intramolecular charge-transfer fluorescence probe: real-time monitoring of mitochondrial ATPase activity.Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome.Roles of Mitochondrial DNA Mutations in Stem Cell Ageing.Multiple Molecular Mechanisms Rescue mtDNA Disease in C. elegans.A novel histochemistry assay to assess and quantify focal cytochrome c oxidase deficiency.Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.

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A Phenotype-Driven Approach to Generate Mouse Models with Pathogenic mtDNA Mutations Causing Mitochondrial Disease.

http://www.wikidata.org/entity/Q37289982

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on September 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

@en

A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

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A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

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A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

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A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

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A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease.

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J.CELREP.2016.08.037

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A Phenotype-Driven Approach to ...... Causing Mitochondrial Disease

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Ana Bratic

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Craig Stamp

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Holly L Baines

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James B Stewart

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Johanna H K Kauppila

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Marie-Lune Simard

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Nils-Göran Larsson

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Roberta Filograna

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P2860

Keeping mtDNA in shape between generations

Premature ageing in mice expressing defective mitochondrial DNA polymerase

Strong purifying selection in transmission of mammalian mitochondrial DNA

The mtDNA-encoded ND6 subunit of mitochondrial NADH dehydrogenase is essential for the assembly of the membrane arm and the respiratory function of the enzyme.

Mitochondrial transcription factor A is necessary for mtDNA maintenance and embryogenesis in mice

Defects in multiple complexes of the respiratory chain are present in ageing human colonic crypts.

Rapid directional shift of mitochondrial DNA heteroplasmy in animal tissues by a mitochondrially targeted restriction endonuclease

Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans

Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs.

Myoclonic epilepsy and ragged-red fiber disease (MERRF) is associated with a mitochondrial DNA tRNA(Lys) mutation.

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2980-2990

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scholarly article

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10.1016/J.CELREP.2016.08.037

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11

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16

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Christoph Freyer

Laura C Greaves

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2016-09-01T00:00:00Z

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27626666

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