Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
about
Retinoids in the pancreasRetinoic acid receptor signaling is required to maintain glucose-stimulated insulin secretion and β-cell mass.Vitamin A deficiency causes hyperglycemia and loss of pancreatic β-cell mass.Insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1.In vitro differentiation of human umbilical cord Wharton's jelly mesenchymal stromal cells to insulin producing clustersVitamin A: a missing link in diabetes?Upregulation of retinoic acid receptor-β reverses drug resistance in cholangiocarcinoma cells by enhancing susceptibility to apoptosis.Retinoic acid receptor β2 agonists restore glycaemic control in diabetes and reduce steatosis.Beta Cell Function and the Nutritional State: Dietary Factors that Influence Insulin Secretion.A retinoic acid receptor β2 agonist reduces hepatic stellate cell activation in nonalcoholic fatty liver disease.RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion.Vitamin A deficiency in mice alters host and gut microbial metabolism leading to altered energy homeostasis.RARβ2-dependent signaling represses neuronal differentiation in mouse ES cells.
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P2860
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 10 June 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
@en
Deletion of retinoic acid receptor β
@nl
type
label
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
@en
Deletion of retinoic acid receptor β
@nl
prefLabel
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.
@en
Deletion of retinoic acid receptor β
@nl
P2860
P1476
Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation
@en
P2093
Lorraine J Gudas
Yannick D Benoit
P2860
P304
P356
10.1016/J.YEXCR.2013.05.032
P407
P577
2013-06-10T00:00:00Z