PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1
about
Protein kinase C signaling and cell cycle regulationDifferential regulation of cyclin D1 expression by protein kinase C α and ϵ signaling in intestinal epithelial cells.Low PKCα expression within the MRD-HR stratum defines a new subgroup of childhood T-ALL with very poor outcome.Protein kinase Cα signaling regulates inhibitor of DNA binding 1 in the intestinal epitheliumC1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosisProtein Kinase Cα (PKCα) Is Resistant to Long Term Desensitization/Down-regulation by Prolonged Diacylglycerol Stimulation.Agonist-induced down-regulation of endogenous protein kinase c α through an endolysosomal mechanism.Heat shock proteins regulate activation-induced proteasomal degradation of the mature phosphorylated form of protein kinase C.Protein kinase Cα suppresses Kras-mediated lung tumor formation through activation of a p38 MAPK-TGFβ signaling axis.Protein kinase C in Wnt signaling: implications in cancer initiation and progression.Protein kinase C and cancer: what we know and what we do not.Nexrutine inhibits azoxymethane-induced colonic aberrant crypt formation in rat colon and induced apoptotic cell death in colon adenocarcinoma cells.Modulation of PKC-α promotes lineage reprogramming of committed B lymphocytes.PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest.MiniSOX9, a dominant-negative variant in colon cancer cells.Protein kinase Cgamma in colon cancer cells: expression, Thr514 phosphorylation and sensitivity to butyrate-mediated upregulation as related to the degree of differentiationStabilization of Sur8 via PKCα/δ degradation promotes transformation and migration of colorectal cancer cells.Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.TGFβ and IGF1R signaling activate protein kinase A through differential regulation of ezrin phosphorylation in colon cancer cells.Protein kinase Cα gain-of-function variant in Alzheimer's disease displays enhanced catalysis by a mechanism that evades down-regulationProtein Kinase C (PKC) Isozymes and Cancer
P2860
Q21131217-8BF76083-D813-4D42-A2BF-6B8A72CFC236Q34070434-6AEF977A-2F50-4D9D-A4B7-487F675D4DB5Q34221792-623CE512-0E6A-486D-8998-60F61D985D9DQ34979083-469491C5-7D71-4D7F-B702-FC5B54B71599Q36149293-5BD1A878-485B-461B-A3A3-45F494B05375Q36744811-7F85A07C-A363-43CC-9821-9CCA3F827162Q36812492-BD7EBE88-843E-4227-8270-EF5B63E6C612Q37189447-84F70878-D4CA-4B35-A7DF-E32461165049Q37491175-311A28D3-7F28-46B9-AB13-3A8FC30C9D3AQ37929700-CB3247A7-5148-4574-A5FB-BC780C39A9DAQ38171231-92D611CD-0398-4AA6-BC55-6827EA1C3824Q38844888-27991E28-8AF1-43ED-95C0-5D8FDEC3B794Q39359221-93ECEFF8-2985-4A09-8BBC-F0D8751388A1Q39375118-F8F9792D-C17B-428B-8A0C-87B4FE28AE4FQ39597052-9A2902AB-1576-4606-9084-AA8EC42E6FC5Q39734373-E3CD11AF-1B54-4F4E-8953-B40F796E2D44Q49312207-CFC5BF8F-45B5-4424-BA11-1E58E978C32DQ49536215-E7E542DD-58BD-4C70-94C4-E99FC89B09F7Q52337636-7EBF8DB3-FF04-46AF-BF85-3CC5C8579D7FQ57825427-5849D972-ACD3-4E2C-B1CE-9018E9595ACFQ59072618-82FEDCCD-4705-4FC9-8B4D-2334C573009F
P2860
PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 February 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
PKCalpha tumor suppression in ...... tional inhibition of cyclin D1
@en
PKCalpha tumor suppression in ...... ional inhibition of cyclin D1.
@nl
type
label
PKCalpha tumor suppression in ...... tional inhibition of cyclin D1
@en
PKCalpha tumor suppression in ...... ional inhibition of cyclin D1.
@nl
prefLabel
PKCalpha tumor suppression in ...... tional inhibition of cyclin D1
@en
PKCalpha tumor suppression in ...... ional inhibition of cyclin D1.
@nl
P2093
P2860
P1476
PKCalpha tumor suppression in ...... tional inhibition of cyclin D1
@en
P2093
Adrian R Black
Anna Velcich
Jennifer D Black
Joshua M Uronis
Kathryn J Curry
Klaus-Peter Janssen
Leonard H Augenlicht
Marybeth A Pysz
Nicholas W Bateman
Olga V Leontieva
P2860
P304
P356
10.1016/J.YEXCR.2009.02.002
P407
P577
2009-02-14T00:00:00Z